Neobavaisoflavone, an isoflavanone derivative, has been reported to display an anti-fungal capacity in vitro. Studies show that this compound can also capable of inhibiting platelet aggregation in rabbit platelets induced by arachidonic acid in vitro. Additional experiments have noted Neobavaisoflavone to be a DNA polymerase inhibitor and an enhancer of TRIAL-induced apoptosis of cells. TRIAL (tumor necrosis factor-related apoptosis-inducing ligand) is an agent that selectively induces programmed cell death in certain cells.
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Bronikowska et alBronikowska et al. (PubMed ID 20336028) found that neobavaisoflavone induced apoptosis in HeLa cells by enhancing TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) cytotoxicity against cancer cells . -SCBT Publication Review
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