NDSB-211 A non-detergent sulfobetaine

NDSB-211 (CAS 38880-58-9)

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Synonym: non-detergent sulfobetaine 211
Application: A non-detergent sulfobetaine
CAS Number: 38880-58-9
Molecular Weight: 211.28
Molecular Formula: C7H17NO4S
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* Refer to Certificate of Analysis for lot specific data (including water content).
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NDSB-211 non-detergent sulfobetaine useful for protein solubilization and stabilization of halophilic proteins. NDSB-211 has been successfully employed to separate halophilic malate dehydrogenase and halophilic bacteria elongation factor Tu by high-performance ion-exchange chromatography without significant loss of activity.


1. Vuillard, L., et al., 1995. Halophilic protein stabilization by the mild solubilizing agents nondetergent sulfobetaines. Analytical biochemistry. 230(2): 290-4. PMID: 7503420
2. Vuillard, L., et al., 1995. Non-detergent sulphobetaines: a new class of mild solubilization agents for protein purification. The Biochemical journal. 305 ( Pt 1)(): 337-43. PMID: 7826351

Physical State :
Solubility :
Soluble in water (50 mg/ml), methanol (5 mg/ml), and DMSO.
Storage :
Store at -20° C
Melting Point :
252-253° C
Boiling Point :
521.96° C (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
EC Number :

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