N9-Isopropyl-olomoucine N9-Isopropyl-olomoucine is an inhibitor of CDK1/cyclin B (IC50 = 2 μM) and CDK5/p35 (IC50 = 3 μM).

N9-Isopropyl-olomoucine  (CAS 158982-15-1)

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Application: An inhibitor of CDK1/cyclin B and CDK5/p35
CAS Number: 158982-15-1
Purity: ≥98%
Molecular Weight: 326.4
Molecular Formula: C17H22N6O
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
N9-Isopropyl-olomoucine sc-202264 1 mg $152.00
N9-Isopropyl-olomoucine sc-202264A 5 mg $555.00

N9-Isopropyl-olomoucine is an inhibitor of CDK1/cyclin B (IC50 = 2 μM) and CDK5/p35 (IC50 = 3 μM).


References

1. Vesely, J., et al. 1994. Eur. J. Biochem. 224: 771-786. PMID: 7925396
2. Raynaud, F.I., et al. 2004. Mol. Cancer Ther. 3: 353-362. PMID: 15026556

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in DMSO, DMF, and methanol (sparingly).
Storage :
Store at -20° C
Melting Point :
230.70° C (Predicted)
Boiling Point :
574.87° C at 760 mmHg (Predicted)
Density :
1.30 g/cm3 (Predicted)
Refractive Index :
n20D 1.66 (Predicted)
IC50 :
CDK1/cyclin B: IC50 = 2 µM; CDK5/p35: IC50 = 3 µM; Cdk2: IC50 = 8 µM
Ki Data :
Cdk5: Ki= 1.26 µM (human); CLK2: Ki= 1.58 µM (human); Cdk2: Ki= 1.58 µM (human); HIPK4: Ki= 2.00 µM (human); CLK4: Ki= 2.5 µM (human)
pK Values :
pKb: 4.76 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
6610355
MDL Number :
MFCD01310377
SMILES :
CC(C)N1C=NC2=C1N=C(N=C2NCC3=CC=CC=C3)NCCO

Download SDS (MSDS)

Certificate of Analysis

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