n-Octyl-β-D-glucopyranoside A nonionic detergent

n-Octyl-β-D-glucopyranoside (CAS 29836-26-8)

n-Octyl-β-D-glucopyranoside | CAS 29836-26-8 is rated 5.0 out of 5 by 1.
  • y_2019, m_5, d_19, h_20
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.12
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_281091, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 82ms
  • REVIEWS, PRODUCT
Synonym: N-Octyl glucoside; OGP
Application: A nonionic detergent
CAS Number: 29836-26-8
Purity: ≥98%
Molecular Weight: 292.34
Molecular Formula: C14H28O6
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

n-Octyl-β-D-glucopyranoside is a non–ionic detergent intended for solubilizing membrane–bound proteins in their native state and for the preparation of lipid vesicles. Its well–defined chemical structure, small uniform micelles, and high water solubility make it superior to most other nonionic detergents for membrane solubilization. Because of its high critical micelle concentration (20-25 mM), n-Octyl-β-D-glucopyranoside has the additional advantage of being removed easily by dialysis when compared to bile salts.


References

1. Lévy, D., et al., 1992. Reconstitution of the sarcoplasmic reticulum Ca(2+)-ATPase: mechanisms of membrane protein insertion into liposomes during reconstitution procedures involving the use of detergents. Biochimica et biophysica acta. 1107(2): 283-98. PMID: 1387003
2. Hoshino, T., et al., 1992. Solubilization and reconstitution of the Pseudomonas aeruginosa high affinity branched-chain amino acid transport system. The Journal of biological chemistry. 267(30): 21313-8. PMID: 1400443
3. Nunn, R S., et al., 1992. Purification and crystallization of the light harvesting LH1 complex from Rhodobacter sphaeroides. Journal of molecular biology. 228(4): 1259-62. PMID: 1474590
4. Lorber, B., et al., 1990. Purification of octyl beta-D-glucopyranoside and re-estimation of its micellar size. Biochimica et biophysica acta. 1023(2): 254-65. PMID: 2328249
5. Jopski, B., et al., 1989. Preparation of hemoglobin-containing liposomes using octyl glucoside and octyltetraoxyethylene. Biochimica et biophysica acta. 978(1): 79-84. PMID: 2914131
6. Gould, R J., et al., 1981. Effects of octyl beta-glucoside on insulin binding to solubilized membrane receptors. Biochemistry. 20(24): 6776-81. PMID: 7032581
7. Camm, E L., et al., 1981. Widespread distribution of some minor chlorophyll-protein complexes in some plants and algae. Plant physiology. 67(5): 1061-3. PMID: 16661784

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (100 mg/ml), methanol, and chloroform(warm).
Storage :
Store at 4° C
Melting Point :
103-104° C
Boiling Point :
454.11° C at 760 mmHg (Predicted)
Density :
1.19 g/cm3 (Predicted)
Refractive Index :
n20D 1.52 (Predicted)
Optical Activity :
α20/D -27°±3°, c = 1 in methanol; α20/D -31°, c = 2 in methanol; α20/D -28.33°, c = 5 in water
IC50 :
BK polyomavirus: EC5050 >100 µM
pK Values :
pKa: 12.95 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
62852
Merck Index :
14: 6767
MDL Number :
MFCD00063288
EC Number :
249-887-8
Beilstein Registry :
84118
SMILES :
CCCCCCCCOC1C(C(C(C(O1)CO)O)O)O

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 74ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Various publications cite the use of the Various publications cite the use of the nonionic detergent n-Octyl- -D-glucopyranoside for solubilizing membrane bound proteins in their native state and for the preparation of lipid vesicles. Because of its high critical micelle concentration (20-25 mM), n-Octyl- -D-glucopyranoside has the additional advantage of being removed easily by dialysis when compared to bile salts. -SCBT Publication Review
Date published: 2015-07-14
  • y_2019, m_5, d_19, h_20
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.12
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_281091, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 221ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.