N-Acetyltryptamine N-Acetyltryptamine is a partial agonist of the melatonin receptors. It is a structural analog of melatonin (sc-207848) lacking the 5-methoxy group.

N-Acetyltryptamine  (CAS 1016-47-3)

N-Acetyltryptamine is rated 5.0 out of 5 by 1.
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Synonym: 3-(2-N-Acetylaminoethyl)indole
Application: A partial agonist for melatonin receptors in the retina
CAS Number: 1016-47-3
Molecular Weight: 202.25
Molecular Formula: C12H14N2O
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
N-Acetyltryptamine sc-202233 10 mg $109.00
N-Acetyltryptamine sc-202233A 50 mg $462.00

N-Acetyltryptamine is a partial agonist of the melatonin receptors. N-Acetyltryptamine bears a reduced structure of Melatonin (sc-207848), lacking the 5-methoxy group. N-Acetyltryptamine is described to demonstrate agonism at melatonin receptors in the rabbit retina, inhibiting Ca2+-dependent release of [3H]dopamine. N-Acetyltryptamine is also described to demonstrate competitive antagonism of the inhibitory effect of melatonin on [3H]dopamine release in the chicken retina.


References

1. Dubocovich, M.L. 1985. J. Pharmacol. Exp. Ther. 234: 395-401. PMID: 2991499
2. Dubocovich, M.L. 1988. J. Pharmacol. Exp. Ther. 246: 902-910. PMID: 2843633

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in alcohol, methanol (50 mg/ml), ethanol (100 mM), and DMSO (100 mM).
Storage :
Store at room temperature
Melting Point :
64° C
Boiling Point :
~484.7° C at 760 mmHg (Predicted)
Density :
~1.2 g/cm3 (Predicted)
Refractive Index :
n20D 1.62 (Predicted)
Ki Data :
Melatonin receptor: Ki= 0.70 µM (Gallus gallus)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
70547
MDL Number :
MFCD00209910
Beilstein Registry :
170780
SMILES :
CC(=O)NCCC1=CNC2=CC=CC=C21

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Worked fine Worked fine.
Date published: 2015-04-08
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