Mycophenolic acid β-D-glucuronide An inhibitor of lymphocyte proliferation via selective IMPDH inhibition

Mycophenolic acid β-D-glucuronide (CAS 31528-44-6)

Mycophenolic acid β-D-glucuronide | CAS 31528-44-6 is rated 5.0 out of 5 by 1.
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Synonym: Mycophenolic Acid Glucosiduronate; Mycophenolic Acid Glucuronide; MPAG
Application: An inhibitor of lymphocyte proliferation via selective IMPDH inhibition
CAS Number: 31528-44-6
Purity: ≥96%
Molecular Weight: 496.46
Molecular Formula: C23H28O12
* Refer to Certificate of Analysis for lot specific data (including water content).
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Mycophenolic Acid β-D-glucuronide is a metabolite of mycophenolic acid (sc-200110). Mycophenolic acid is an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. and a selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase.


References

Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999).

Physical State :
Solid
Solubility :
Soluble in methanol, and water.
Storage :
Store at -20° C
Melting Point :
98-100° C
Boiling Point :
~875.7° C at 760 mmHg (Predicted)
Density :
~1.5 g/cm3 (Predicted)
Refractive Index :
n20D 1.63 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
6442661
MDL Number :
MFCD09878308
SMILES :
CC1=C(C(=C(C2=C1COC2=O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)O)O)O)O)C/C=C(\\C)/CCC(=O)O)OC

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Mycophenolic acid β Mycophenolic acid β-D-glucuronide was reported in many articles as a metabolite of Mycopholic acid that is mostly metabolized in the liver. -SCBT Publication Review
Date published: 2015-04-18
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