MTSET-Chloride A probe fore ACh receptor channel of the GABAA receptor channel

MTSET-Chloride (CAS 210167-37-6)

MTSET-Chloride | CAS 210167-37-6 (free base) is rated 5.0 out of 5 by 1.
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Synonym: [2-(Trimethylammonium)ethyl] Methanethiosulfonate Chloride
Application: A probe fore ACh receptor channel of the GABAA receptor channel
CAS Number: 210167-37-6
Molecular Weight: 233.78
Molecular Formula: C6H16ClNO2S2
* Refer to Certificate of Analysis for lot specific data (including water content).
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MTSET-Chloride reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABAA receptor channel and of lactose permease.


References

Duhten, R.L., et al.: Biochemistry, 32, 3139 (1993), Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996), Holmgren, M. et al: Neuropharmacology, 35, 797 (1996), Chahine, M. et al.: Biochemical & Biophysical Res. Commun., 233, 606 (1997), Ehrlich, B.E., et al.: J. Gen. Physiol., 109, 255 (1997), Rassendren, F., et al.: The EMBO Journal, 16, 3446 (1997), Vedantham, V.

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in DMSO, Methanol and Water
Storage :
Store at -20° C
Melting Point :
180-182° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
71752821
SMILES :
C[N+](C)(C)CCSS(=O)(=O)C.[Cl-]

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Certificate of Analysis

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Rated 5 out of 5 by from Various publications cite the use of MTSET Various publications cite the use of MTSET-Chloride to probe the structures of the ACh receptor channel of the GABAA receptor channel and of lactose permease. -SCBT Publication Review
Date published: 2015-04-11
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