MRG1 Antibody (JA22) is a mouse monoclonal IgG1 (kappa light chain) provided at 200 µg/ml
raised against amino acids 66-270 of human MRG1, requires amino acids 66-124 for recognition
recommended for detection of MRG1 of mouse, rat and human origin by WB, IP, IF and IHC(P)
available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
TransCruz reagent for Gel Supershift and ChIP applications (sc-21795 X, 200 µg/0.1 ml)
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of MRG1 (JA22): sc-21795.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MRG1 (MSG1-related gene 1) is a primary response gene that shares substantial sequence similarity to the carboxy-terminal region of MSG1 (melanocyte-specific gene-1). Both MRG1 and MSG1 contain two conserved domains designated CR1 and CR2, the latter of which is required for transcriptional activation, and they appear to represent a unique family of transcription factors. MRG1 expression is induced by cytokines, including IL-1a, IL-9, and GM-CSF, as well as by serum growth factors, and it is regulated by the JAK/ Stat pathway. Overexpression of MRG1 induces anchorage-independent growth in soft agar, loss of cell contact inhibition and tumor formation in nude mice, suggesting that MRG1 is a transforming gene with oncogenic properties. A splice variant of MRG1, designated p35srj, is ubiquitously expressed and interacts with the p300-CH1 domain of p300/CBP, where it inhibits the interaction of p300/CBP with hypoxia-inducible factor-1a (HIF-1a) to prevent HIF-1 transactivation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
When should the TransCruz reagent sc-21795 X be used instead of the standard form sc-21795?
Asked by: jenni
Thank you for your question. We recommend using the TransCruz reagent form when performing ChIP or GelShift assays. This form can also be used in other applications such as Western Blot or IHC, but the dilution should be adjusted by a factor of 10 to account for the higher original concentration.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
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