MOPS solution A morpholino propanesulfonic acid buffer

MOPS solution (CAS 1132-61-2)

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Application: A morpholino propanesulfonic acid buffer
CAS Number: 1132-61-2
Molecular Weight: 209.26
Molecular Formula: C7H15NO4S
* Refer to Certificate of Analysis for lot specific data (including water content).

MOPS is a morpholino propanesulfonic acid, a structural analog to MES, the ethanesulfonic acid (first introduced by Good et al.) Both series of buffers were developed to meet the following criteria: midrange pKa, maximum water solubility and minimum solubility in all other solvents, minimal salt effects, minimal change in pKa with temperature chemically and enzymatically stable, minimal absorption in visible or UV spectral range, and reasonably easily synthesized. pKa=7.2 at 25°C, Effective buffering range.


1. Good, N.E. et al. 1966. Biochemistry. 5(2): 467-477. PMID: 5942950
2. Thomas, J.M. and Hodes, M.E. 1981. Anal. Biochem. 118(1): 194-196. PMID: 6278979
3. Ellis, K.J. and Morrison, J.F. 1982. Meth. Enzymol. 87 : 405-426. PMID: 7176924

Formulation :
1 M
Appearance :
Physical State :
Solubility :
Soluble in water (1 M), and ethanol (<10 g/l) at 20 °C.
pH :
useful range: 6.5 - 7.9
Storage :
Store at room temperature
Refractive Index :
n20D 1.51 (Predicted)
pK Values :
pKa: 7.2 (at 25°C), pKb: 6.27
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 6265
MDL Number :
EC Number :
Beilstein Registry :

Download SDS (MSDS)

Certificate of Analysis

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