MOPS, Sodium3-(N-Morpholino)propanesulfonic Acid, Na; an analog to MES used in polyacrylamide gel electrophoresis

MOPS, Sodium (CAS 71119-22-7)

MOPS, Sodium | CAS 71119-22-7 is rated 5.0 out of 5 by 1.
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Synonym: 4-Morpholinepropanesulfonic acid sodium salt
Application: 3-(N-Morpholino)propanesulfonic Acid, Na; an analog to MES used in polyacrylamide gel electrophoresis
CAS Number: 71119-22-7
Purity: ≥98%
Molecular Weight: 231.2
Molecular Formula: C7H14NO4S•Na
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

MOPS [3-(N-Morpholino)propanesulfonic Acid] is a morpholino propanesulfonic acid, and structural analog to MES (first introduced by Good et al.) Both series of buffers were developed to meet the following criteria: midrange pKa, maximum water solubility, minimum solubility in all other solvents, minimal salt effects, minimal change in pKa with temperature chemically and enzymatically stable, minimal absorption in visible or UV spectral range, and reasonably is easily synthesized. pKa=7.2 at 25°C, Effective buffering range: pH 6.5-8.0.


References

1. Ellis, K.J. and Morrison, J.F. 1982. Methods Enzymol. 87: 405-426. PMID: 7176924
2. Good, N.E., et al. 1966. Biochemistry. 5: 467-477. PMID: 5942950
3. Tucker, D.L., et al. 2002. J. Bacteriol. 184: 6551-6558. PMID: 12426343
4. Petrou, M.A. and Shanson, D.C. 2000. J. Antimicrob. Chemother. 46: 815-818. PMID: 11062205

Usage :
• This product is a high quality reagent, but has not been evaluated for use in cell culture. Please employ appropriate contaminant testing and/or sterilization techniques for the intended application.
Physical State :
Solid
Solubility :
Soluble in water (523 g/l at 20° C).
Storage :
Store at room temperature
Melting Point :
220.9° C
Density :
1.41 g/cm3 at 20° C
Refractive Index :
n20D ~1.51 (Predicted)
pK Values :
pKa: 7.2 (25° C)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
PubChem CID :
3859613
Merck Index :
14: 6265
MDL Number :
MFCD00064350
SMILES :
C1COCCN1CCCS(=O)(=O)[O-].[Na+]

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Akram AC; et al Akram AC; et al. (PubMed ID: 25555225) determined that MOPS, Sodium is a buffer that causes the least spontaneous fluorescein diacetate breakdown without inhibiting enzymatic activity. -SCBT Publication Review
Date published: 2015-06-27
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