|PRODUCT NAME||CATALOG #||UNIT||PRICE||QTY||FAVORITES|
|Monosodium urate (crystals)||sc-202711||2 mg||$90.00||
Monosodium urate has been reported to be an inflammatory compound. Mechanistic studies suggest that this compound intracellularly engages caspase-1-activating cryopyrin inflammasome, resulting in the production of active IL-1β and IL-18. Experiments have shown that monosodium urate crystals also induce triggering receptor expressed on myeloid cells 1 (TREM-1) expression in infiltrating leukocytes in a murine air-pouch model of crystal-induced acute inflammation. Monosodium urate is also an activator of cryopyrin.
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See how others have used Monosodium urate (crystals). Click on the entry to view the PubMed entry .
PMID: # 24121974
Liu, W. et al. 2014. OxLDL-induced IL-1 beta secretion promoting foam cells formation was mainly via CD36 mediated ROS production leading to NLRP3 inflammasome activation. Inflamm. Res.. 63: 33-43.
PMID: # 24574460
Taylor, A. et al. 2014. SRF is required for neutrophil migration in response to inflammation. Blood. 123: 3027-36.
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