Miconazole Nitrate An antifungal agent that inhibits platelet cyclooxygenase

Miconazole Nitrate (CAS 22832-87-7)

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Synonym: NSC 169434; R 14889; (±)-Miconazole nitrate salt
Application: An antifungal agent that inhibits platelet cyclooxygenase
CAS Number: 22832-87-7
Purity: ≥98%
Molecular Weight: 479.15
Molecular Formula: C18H14Cl4N2O•HNO3
* Refer to Certificate of Analysis for lot specific data (including water content).
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Miconazole Nitrate is a topical antifungal agent found to inhibit platelet cyclooxygenase.


References

Ishikawa S, Manabe S, Wada O. Biochem Pharmacol. 35:1787-92 (1986). Sweeny WT. Vet Med Small Anim Clin. 70:1438-40 (1975).

Physical State :
Solid
Solubility :
Soluble in DMSO (96 mg/ml at 25° C), methanol, water (<1 mg/ml at 25° C), ethanol (10 mM), and pyridine (50 mg/ml).
Storage :
Store at room temperature
Refractive Index :
n20D ~1.63 (Predicted)
Optical Activity :
α25/D 0°, c = 10 in water
IC50 :
Mycobacterium tuberculosis H37Rv.: IC50 = 2.85 µM; Methionyl-tRNA synthetase, putative: IC50 = 11.05 µM (Trypanosoma brucei brucei )
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
NI4771000
PubChem CID :
68553
Merck Index :
14: 6178
MDL Number :
MFCD00058161
EC Number :
245-256-6
SMILES :
C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl.[N+](=O)(O)[O-]

Download SDS (MSDS)

Certificate of Analysis

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