Micafungin (CAS 235114-32-6)
Synonym:
Mycamine
Application:
A semi-synthetic cyclic lipopeptide of the echinocandin class
CAS Number:
235114-32-6
Purity:
≥98%
Molecular Weight:
1270.27
Molecular Formula:
C56H71N9O23S
* Refer to Certificate of Analysis for lot specific data (including water content).
Micafungin is a semi-synthetic cyclic lipopeptide belonging to the echinocandin class. Unlike other marketed semi-synthetic derivatives in this class, micafungin is not derived from echinocandin but rather from FR901379, which contains a phenolic sulphate to enhance aqueous solubility, a serious limitation in the class. Micafungin's antifungal properties stem from its ability to inhibit the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall in susceptible fungi.
Physical State
:
Solid
Derived From
:
Semi-synthetic
Solubility
:
Soluble in ethanol, methanol, DMF, DMSO, and water (moderately).
Storage
:
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS
:
TP7846500
PubChem CID
:
477468
MDL Number
:
MFCD09837852
Beilstein Registry
:
9610508
SMILES
:
CCCCCOC1=CC=C(C=C1)C2=CC(=NO2)C3=CC=C(C=C3)C(=O)N[C@H]4C[C@H]([C@H](NC(=O)[C@@H]5[C@H]([C@H](CN5C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]6C[C@H](CN6C(=O)[C@@H](NC4=O)[C@@H](C)O)O)[C@@H]([C@H](C7=CC(=C(C=C7)O)OS(=O)(=O)O)O)O)[C@@H](CC(=O)N)O)C)O)O)O
Download SDS (MSDS)
Certificate of Analysis
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Rated 5 out of
5
by
TO from
Gil
Gil-Alonso, S. et al. (PubMed 26168269) studied the post-anti-fungal effects (PAFE) of Micafungin (Mycamine), an effective anti-fungal agent, against several non-C. albicans species. They found that Micafungin showed longer PAFE for C. albicans compared to other non-C. albicans species. -SCBT Publication Review
Date published: 2015-05-26
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