Methicillin Sodium Salt A semi-synthetic antibiotic related to penicillin

Methicillin Sodium Salt (CAS 132-92-3)

Methicillin Sodium Salt | CAS 132-92-3 is rated 5.0 out of 5 by 1.
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Synonym: Sodium (2,6-dimethoxyphenyl)penicillin; Sodium methicillin
Application: A semi-synthetic antibiotic related to penicillin
CAS Number: 132-92-3
Purity: ≥85%
Molecular Weight: 402.39
Molecular Formula: C17H19N2O6S•Na
* Refer to Certificate of Analysis for lot specific data (including water content).
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Methicillin Sodium Salt is a narrow spectrum β-lactam antibiotic in the penicillin family. β-lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP's are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Methicillin Sodium Salt is inactivated by gastric acid so it is given to cells by other means in which gastric acid is not present in vitro.

Physical State :
Solid
Storage :
Store at -20° C
Melting Point :
196-197 °C (dec.)
Boiling Point :
640 °C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
RTECS :
XH8950000
PubChem CID :
23667627
Merck Index :
14: 5969
MDL Number :
MFCD07787409
EC Number :
205-083-9
SMILES :
CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)C3=C(C=CC=C3OC)OC)C(=O)[O-])C. [Na+]

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Vigo Vigo, GB. et al. (PubMed 26323373) found that 10.7% of Staphylococcus pseudintermedius strains, isolated from dog clinical samples, showed resistance to Methicillin, semi-synthetic antibiotic related to penicillin. -SCBT Publication Review
Date published: 2015-06-21
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