MES, Sodium SaltA buffering agent used in biological and biochemical research including plant cell culture

MES, Sodium Salt (CAS 71119-23-8)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 70ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: sodium 2-(4-morpholinyl)ethanesulfonate; Sodium 2-Morpholinoethanesulfonate
Application: A buffering agent used in biological and biochemical research including plant cell culture
CAS Number: 71119-23-8
Purity: ≥99%
Molecular Weight: 217.22
Molecular Formula: C6H12NO4S•Na
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

MES, Sodium Salt (2-(N-Morpholino)ethanesulfonic acid sodium salt) is a zwitterionic N-substituted aminosulfonic acid known as a Good's buffer, active in the pH range 6-8 with a pKa of 6.10 at 25° C. With a pKa value near physiological pH, it is not absorbed through cell membranes, and it is essentially transparent to UV light. MES is used as a running buffer for resolving very small proteins (ex: 13 kDa) on bis-tris gels. Also used in cation-exchange chromatography and as a biological buffer in plant cell cultures. MES solutions can be prepared to the desired pH by titrating the free acid with sodium hydroxide.

Also available: MES hydrate (sc-216094); MES hemisodium salt (sc-216093); MES solution (sc-300959).


References

1. Good, N.E., et al. 1966. Biochemistry. 5: 467-477. PMID: 5942950
2. Graf, H., et al. 1994. Bioseparation. 4: 7-20. PMID: 7764588
3. Anfossi, L., et al. 2003. Ann Chim. 93: 499-512. PMID: 12911143
4. Mönch, S., et al. 2010. Anal. Biochem. 398: 150-160. PMID: 19903444
5. Teste, B., et al. 2010. Talanta. 81: 1703-1710. PMID: 20441961

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (0.5 g/l).
Storage :
Store at 4° C
pK Values :
pKa: 6.1
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
PubChem CID :
23673676
MDL Number :
MFCD00065473
EC Number :
275-203-2
Beilstein Registry :
3765682
SMILES :
C1COCCN1CCS(=O)(=O)[O-].[Na+]

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 82ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 36ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.