Meropenem with sodium carbonate A product for proteomics research

Meropenem with sodium carbonate (CAS 96036-03-2 (free acid))

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 59ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: (4R,5S,6S)-3-[[(3S,5S)5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-carboxyloc acid
Application: A product for proteomics research
CAS Number: 96036-03-2 (free acid)
Molecular Weight: 383.46 (free acid)
Molecular Formula: C17H25N3O5S•xNa2CO3
* Refer to Certificate of Analysis for lot specific data (including water content).
submit a review for this product and receive 15 cruzcredits

Meropenem with sodium carbonate is a salt form of Meropenem, a β-lactam antibiotic of the carbapenem subclass that has been shown to inhibit penicillinase-negative, -positive and methicillin-susceptible staphylococci. This compound demonstrates the ability to also affect strains of 11 species of streptococci. Mechanistic studies suggest that Meropenem's antimicrobial activity is based on its high affinity for the majority of penicillin-binding proteins, which are cell wall-synthesizing enzymes. Meropenem is very effective because it resists inactivation by the majority of microbial LACTB (β-lactamases) as well as kidney dehydropeptidase I. Experiments have shown Meropenem to have a low toxicity profile and, in contrast to similar compounds, no central nervous system toxicity.


References

1. Honorato, J., et al., 1997. [Clinical pharmacology and indications of meropenem in severe pediatric infection]. Enfermedades infecciosas y microbiología clínica. 15 Suppl 1(): 38-44. PMID: 9410068
2. Cottagnoud, P., et al., 2002. Cellular and molecular aspects of drugs of the future: meropenem. Cellular and molecular life sciences : CMLS. 59(11): 1928-33. PMID: 12530523
3. Nicolau, David P., et al., 2008. Pharmacokinetic and pharmacodynamic properties of meropenem. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 47 Suppl 1(): S32-40. PMID: 18713048

Physical State :
Solid
Storage :
Store at room temperature
Optical Activity :
α20/D -19º±2º, c = 1 in water
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
MDL Number :
MFCD08600005
SMILES :
CC1C2C(C(=O)N2C(=C1SC3CC(NC3)C(=O)N(C)C)C(=O)O)C(C)O.O.O.O.[Na+].[Na+].[O-]C([O-])=O

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 159ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 5ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.