MCPyV large T-antigen Antibody (CM2B4)
  • MCPyV large T-antigen Antibody (CM2B4) is a mouse monoclonal mouse IgG2b κ (kappa light chain) provided at 200 µg/ml
  • raised against large T/57kT exon 2 peptides of Merkel cell polyomavirus
  • recommended for detection of Merkel Cell Polyomavirus by WB, IP, IF and IHC(P)
  • available conjugated to agarose (sc-136172 AC), 500 µg/0.25 ml agarose in 1 ml, for IP; HRP (sc-136172 HRP), 200 µg/ml, for WB, IHC(P) and ELISA; and to either phycoerythrin (sc-136172 PE) or fluorescein (sc-136172 FITC), 200 µg/ml, for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488 (sc-136172 AF488), Alexa Fluor® 594 (sc-136172 AF594) or Alexa Fluor® 647 (sc-136172 AF647), 200 µg/ml, for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 680 (sc-136172 AF680) or Alexa Fluor® 790 (sc-136172 AF790), 200 µg/ml, for WB (NIR), IF and FCM; suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR®/Odyssey® and other comparable systems
  • See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) (sc-516102), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
  • Achieve better research results using superior monoclonal antibodies from Santa Cruz! Contact us to receive a FREE 10 µg sample of MCPyV large T-antigen (CM2B4): sc-136172.

MCPyV large T-antigen Antibody (CM2B4): sc-136172

MCPyV large T-antigen Antibody (CM2B4) is rated 3.8 out of 5 by 6.
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Datasheets
    • MCPyV large T-antigen Antibody (CM2B4) is a mouse monoclonal mouse IgG2b κ (kappa light chain) provided at 200 µg/ml
    • raised against large T/57kT exon 2 peptides of Merkel cell polyomavirus
    • recommended for detection of Merkel Cell Polyomavirus by WB, IP, IF and IHC(P)
    • available conjugated to agarose (sc-136172 AC), 500 µg/0.25 ml agarose in 1 ml, for IP; HRP (sc-136172 HRP), 200 µg/ml, for WB, IHC(P) and ELISA; and to either phycoerythrin (sc-136172 PE) or fluorescein (sc-136172 FITC), 200 µg/ml, for IF, IHC(P) and FCM
    • also available conjugated to Alexa Fluor® 488 (sc-136172 AF488), Alexa Fluor® 594 (sc-136172 AF594) or Alexa Fluor® 647 (sc-136172 AF647), 200 µg/ml, for IF, IHC(P) and FCM
    • also available conjugated to Alexa Fluor® 680 (sc-136172 AF680) or Alexa Fluor® 790 (sc-136172 AF790), 200 µg/ml, for WB (NIR), IF and FCM; suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR®/Odyssey® and other comparable systems
    • See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) (sc-516102), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
    • Achieve better research results using superior monoclonal antibodies from Santa Cruz! Contact us to receive a FREE 10 µg sample of MCPyV large T-antigen (CM2B4): sc-136172.
Submit a review for this product and receive 15 CruzCredits

Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
MCPyV large T-antigen Antibody (CM2B4) sc-136172 200 µg/ml $279.00
MCPyV large T-antigen Antibody (CM2B4) AC sc-136172 AC 500 µg/ml, 25% ag $366.00
MCPyV large T-antigen Antibody (CM2B4) HRP sc-136172 HRP 200 µg/ml $279.00
MCPyV large T-antigen Antibody (CM2B4) FITC sc-136172 FITC 200 µg/ml $292.00
MCPyV large T-antigen Antibody (CM2B4) PE sc-136172 PE 200 µg/ml $303.00
MCPyV large T-antigen Antibody (CM2B4) Alexa Fluor® 488 sc-136172 AF488 200 µg/ml $314.00
MCPyV large T-antigen Antibody (CM2B4) Alexa Fluor® 594 sc-136172 AF594 200 µg/ml $314.00
MCPyV large T-antigen Antibody (CM2B4) Alexa Fluor® 647 sc-136172 AF647 200 µg/ml $314.00
MCPyV large T-antigen Antibody (CM2B4) Alexa Fluor® 680 sc-136172 AF680 200 µg/ml $314.00
MCPyV large T-antigen Antibody (CM2B4) Alexa Fluor® 790 sc-136172 AF790 200 µg/ml $314.00

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MCPyV large T-antigen Antibody (CM2B4)Product Citations

See how others have used MCPyV large T-antigen Antibody (CM2B4). Click on the entry to view the PubMed entry .

Citations 1 to 10 of 29 total

PMID: # 27166398
Feldmeyer, L. et al. 2016. Density, Distribution, and Composition of Immune Infiltrates Correlate with Survival in Merkel Cell Carcinoma. Clin. Cancer Res..

PMID: # 27774637
Chou, TC. et al. 2016. Presence of the Merkel cell polyomavirus in Merkel cell carcinoma combined with squamous cell carcinoma in a patient with chronic arsenism. Clin. Exp. Dermatol.. 41: 902-905.

PMID: # 27392929
Alos, L. et al. 2016. p16 overexpression in high-grade neuroendocrine carcinomas of the head and neck: potential diagnostic pitfall with HPV-related carcinomas. Virchows Arch.. 469: 277-84.

PMID: # 26383606
Schrama, D. et al. 2016. Serine 220 phosphorylation of the Merkel cell polyomavirus large T antigen crucially supports growth of Merkel cell carcinoma cells. International journal of cancer. Journal international du cancer. 138: 1153-62.

PMID: # 26608318
Tsang, SH. et al. 2015. The Oncogenic Small Tumor Antigen of Merkel Cell Polyomavirus Is an Iron-Sulfur Cluster Protein That Enhances Viral DNA Replication. J. Virol.. 90: 1544-56.

PMID: # 25480786
Li, J. et al. 2015. Phosphorylation of Merkel cell polyomavirus large tumor antigen at serine 816 by ATM kinase induces apoptosis in host cells. The Journal of biological chemistry. 290: 1874-84.

PMID: # 25208506
Houben, et al. 2015. Characterization of functional domains in the Merkel cell polyoma virus Large T antigen International Journal of Cancer. 136: E290-300.

PMID: # 25623078
Leroux-Kozal, V. et al. 2015. Merkel cell carcinoma: histopathologic and prognostic features according to the immunohistochemical expression of Merkel cell polyomavirus large T antigen correlated with viral load. Hum. Pathol.. 46: 443-53.

PMID: # 26600395
Samimi, M. et al. 2015. Prognostic value of antibodies to Merkel cell polyomavirus T-Antigens and VP1 protein in Merkel cell carcinoma patients. Br. J. Dermatol..

PMID: # 25006834
Diaz, J. et al. 2014. Phosphorylation of large T antigen regulates merkel cell polyomavirus replication. Cancers. 6: 1464-86.

Citations 1 to 10 of 29 total

What is the recommended secondary reagent to be used with this mouse monoclonal primary?

Asked by: jerojero
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Tech Service 3
Date published: 2016-12-22
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Rated 5 out of 5 by from Great This antibody is very good for IF staining. The background is very low.
Date published: 2017-08-15
Rated 5 out of 5 by from Published results in IHC Works very well for IHC purposes. I've had this antibody for over a year and it still works amazingly well.
Date published: 2017-02-08
Rated 4 out of 5 by from Well published Established monoclonal antibody for MCPyV large T-antigen, well published for Western Blot and IF.
Date published: 2016-12-22
Rated 3 out of 5 by from Worked well with transfected lysate by WB Worked well with transfected lysate by WB -SCBT QC
Date published: 2015-06-19
Rated 1 out of 5 by from Obtained false positive results in IF Obtained false positive results in IF.
Date published: 2015-06-16
Rated 5 out of 5 by from Publishable results in my WB Publishable results in my WB.
Date published: 2015-03-26
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