MCPyV large T-antigen Antibody (CM2B4)
  • MCPyV large T-antigen Antibody (CM2B4) is a mouse monoclonal IgG2b (kappa light chain) provided at 200 µg/ml
  • raised against large T/57kT exon 2 peptides of Merkel cell polyomavirus
  • recommended for detection of Merkel Cell Polyomavirus by WB, IP, IF and IHC(P)
  • available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or fluorescein for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
  • Contact us to receive a FREE 10 µg sample of MCPyV large T-antigen (CM2B4): sc-136172.
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MCPyV large T-antigen Antibody (CM2B4): sc-136172

MCPyV large T-antigen Antibody (CM2B4) is rated 4.0 out of 5 by 7.
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Datasheets
    • MCPyV large T-antigen Antibody (CM2B4) is a mouse monoclonal IgG2b (kappa light chain) provided at 200 µg/ml
    • raised against large T/57kT exon 2 peptides of Merkel cell polyomavirus
    • recommended for detection of Merkel Cell Polyomavirus by WB, IP, IF and IHC(P)
    • available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or fluorescein for IF, IHC(P) and FCM
    • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
    • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
    • See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
    • Contact us to receive a FREE 10 µg sample of MCPyV large T-antigen (CM2B4): sc-136172.
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Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
MCPyV large T-antigen Antibody (CM2B4) sc-136172 200 µg/ml $279.00
MCPyV large T-antigen Antibody (CM2B4) AC sc-136172 AC 500 µg/ml, 25% agarose $366.00
MCPyV large T-antigen Antibody (CM2B4) HRP sc-136172 HRP 200 µg/ml $279.00
MCPyV large T-antigen Antibody (CM2B4) FITC sc-136172 FITC 200 µg/ml $292.00
MCPyV large T-antigen Antibody (CM2B4) PE sc-136172 PE 200 µg/ml $303.00
MCPyV large T-antigen Antibody (CM2B4) Alexa Fluor® 488 sc-136172 AF488 200 µg/ml $314.00
MCPyV large T-antigen Antibody (CM2B4) Alexa Fluor® 546 sc-136172 AF546 200 µg/ml $314.00
MCPyV large T-antigen Antibody (CM2B4) Alexa Fluor® 594 sc-136172 AF594 200 µg/ml $314.00
MCPyV large T-antigen Antibody (CM2B4) Alexa Fluor® 647 sc-136172 AF647 200 µg/ml $314.00
MCPyV large T-antigen Antibody (CM2B4) Alexa Fluor® 680 sc-136172 AF680 200 µg/ml $314.00
MCPyV large T-antigen Antibody (CM2B4) Alexa Fluor® 790 sc-136172 AF790 200 µg/ml $314.00

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MCPyV large T-antigen Antibody (CM2B4)Product Citations

See how others have used MCPyV large T-antigen Antibody (CM2B4). Click on the entry to view the PubMed entry .

Citations 1 to 10 of 32 total

PMID: # 29273486
Kervarrec, T. et al. 2017. Merkel cell carcinomas infiltrated with CD33+myeloid cells and CD8+T cells are associated with improved outcome. Journal of the American Academy of Dermatology.

PMID: # 29180096
Kervarrec, T. et al. 2017. Differentiating Merkel cell carcinoma of lymph nodes without a detectable primary skin tumor from other metastatic neuroendocrine carcinomas: The ELECTHIP criteria. Journal of the American Academy of Dermatology.

PMID: # 27166398
Feldmeyer, L. et al. 2016. Density, Distribution, and Composition of Immune Infiltrates Correlate with Survival in Merkel Cell Carcinoma. Clin. Cancer Res..

PMID: # 27774637
Chou, TC. et al. 2016. Presence of the Merkel cell polyomavirus in Merkel cell carcinoma combined with squamous cell carcinoma in a patient with chronic arsenism. Clin. Exp. Dermatol.. 41: 902-905.

PMID: # 27392929
Alos, L. et al. 2016. p16 overexpression in high-grade neuroendocrine carcinomas of the head and neck: potential diagnostic pitfall with HPV-related carcinomas. Virchows Arch.. 469: 277-84.

PMID: # 26383606
Schrama, D. et al. 2016. Serine 220 phosphorylation of the Merkel cell polyomavirus large T antigen crucially supports growth of Merkel cell carcinoma cells. International journal of cancer. Journal international du cancer. 138: 1153-62.

PMID: # 26608318
Tsang, SH. et al. 2015. The Oncogenic Small Tumor Antigen of Merkel Cell Polyomavirus Is an Iron-Sulfur Cluster Protein That Enhances Viral DNA Replication. J. Virol.. 90: 1544-56.

PMID: # 25480786
Li, J. et al. 2015. Phosphorylation of Merkel cell polyomavirus large tumor antigen at serine 816 by ATM kinase induces apoptosis in host cells. The Journal of biological chemistry. 290: 1874-84.

PMID: # 25208506
Houben, et al. 2015. Characterization of functional domains in the Merkel cell polyoma virus Large T antigen International Journal of Cancer. 136: E290-300.

PMID: # 25623078
Leroux-Kozal, V. et al. 2015. Merkel cell carcinoma: histopathologic and prognostic features according to the immunohistochemical expression of Merkel cell polyomavirus large T antigen correlated with viral load. Hum. Pathol.. 46: 443-53.

Citations 1 to 10 of 32 total

What is the recommended secondary reagent to be used with this mouse monoclonal primary?

Asked by: jerojero
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Tech Service 3
Date published: 2016-12-22
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Rated 5 out of 5 by from CM2B4 CM2B4 gave a nice signal in about 60% of our tumor samples (MCC)
Date published: 2018-03-23
Rated 5 out of 5 by from Great This antibody is very good for IF staining. The background is very low.
Date published: 2017-08-15
Rated 5 out of 5 by from Published results in IHC Works very well for IHC purposes. I've had this antibody for over a year and it still works amazingly well.
Date published: 2017-02-08
Rated 4 out of 5 by from Well published Established monoclonal antibody for MCPyV large T-antigen, well published for Western Blot and IF.
Date published: 2016-12-22
Rated 3 out of 5 by from Worked well with transfected lysate by WB Worked well with transfected lysate by WB -SCBT QC
Date published: 2015-06-19
Rated 1 out of 5 by from Obtained false positive results in IF Obtained false positive results in IF.
Date published: 2015-06-16
Rated 5 out of 5 by from Publishable results in my WB Publishable results in my WB.
Date published: 2015-03-26
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