LY 344864 hydrochlorideA potent and selective SR-1F agonist

LY 344864 hydrochloride (CAS 186544-26-3)

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Application: A potent and selective SR-1F agonist
CAS Number: 186544-26-3
Purity: >99%
Molecular Weight: 387.88
Molecular Formula: C21H22N3OF.HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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LY 344864 hydrochloride is a potent and selective SR-1F agonist with an EC50 of 3 nM. This compound has been shown to display > 80-fold selectivity over other serotonin receptors (Ki values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 µM for SR-1F, SR-1A, SR-1B, SR-1D, SR-1E, SR-2B, SR-2C, SR-2A, and SR-7, respectively). Furthermore LY 344864 hydrochloride has been shown to inhibit neurogenic dural inflammation in vivo.

Solubility :
Soluble to 50 mM in water and to 100 mM in DMSO
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Certificate of Analysis

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