Lotaustralin A carbohydrate derivative

Lotaustralin (CAS 534-67-8)

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Synonym: 2(R)-Hydroxy-2-methylbutyronitrile-beta-D-glucopyranoside
Application: A carbohydrate derivative
CAS Number: 534-67-8
Molecular Weight: 261.27
Molecular Formula: C11H19NO6
* Refer to Certificate of Analysis for lot specific data (including water content).
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Lotaustralin is a cyanogenic glucoside found in trace amounts in a wide variety of plants. Lotaustralin is the glucoside of methyl ethyl ketone cyanohydrin and is structurally related to linamarin, an acetone cyanohydrin glucoside also found in plants. Both lotaustralin and linamarin may be hydrolyzed by the enzyme linamarase to form glucose and a precursor to the toxic compound hydrogen cyanide.


References

1. Yoshikawa, M., et al., 1997. Bioactive constituents of Chinese natural medicines. IV. Rhodiolae radix. (2).: On the histamine release inhibitors from the underground part of Rhodiola sacra (Prain ex Hamet) S. H. Fu (Crassulaceae): chemical structures of rhodiocyanoside D and sacranosides A and B. Chemical & pharmaceutical bulletin. 45(9): 1498-503. PMID: 9332002

Physical State :
Solid
Solubility :
Soluble in DMSO and Methanol
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
441467
SMILES :
CC[C@](C)(C#N)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O

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Certificate of Analysis

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Lotaustralin  Product Citations

See how others have used Lotaustralin. Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 25350522  Sulyok, M. et al. 2015. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 32: 488-502.

PMID: # 24863488  Shlichta, JG. et al. 2014. Journal of chemical ecology. 40: 468-75.

Citations 1 to 2 of 2 total

What is the purity of this product? >95%?

Asked by: Michael G
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate Of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate Of Analysis on our website. Alternatively, please contact our Technical Service Department to inquire about the purity of our most recent lot.
Answered by: Technical Support
Date published: 2018-12-21

What is the solubility of this product?

Asked by: hawkeye11
This chemical, Lotaustralin (CAS 534-67-8), will dissolve in Water at ~3mg/ml and in Methanol at ~3mg/ml.
Answered by: Chemical Support 1
Date published: 2017-03-09
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