Lipopolysaccharide, Ultra Pure, Salmonella minnesota R595 (Re)A phenol-petroleum ether

Lipopolysaccharide, Ultra Pure, Salmonella minnesota R595 (Re)

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Application: A phenol-petroleum ether
* Refer to Certificate of Analysis for lot specific data (including water content).
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Lipopolysaccharide, Ultra Pure, Salmonella minnesota R595 (Re) is a phenol-petroleum ether extracted lipopolysaccharide (LPS) containing 0.3% proteins. LPS 595 (Re) has been shown to stimulate TLR4 (Toll-like receptor-4), but not TLR2, signaling in human cell lines.


References

1. Galanos, C., et al., 1969. A new method for the extraction of R lipopolysaccharides. European journal of biochemistry / FEBS. 9(2): 245-9. PMID: 5804498
2. Hirschfeld, M., et al., 2000. Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. Journal of immunology (Baltimore, Md. : 1950). 165(2): 618-22. PMID: 10878331
3. Tapping, R I., et al., 2000. Toll-like receptor 4, but not toll-like receptor 2, is a signaling receptor for Escherichia and Salmonella lipopolysaccharides. Journal of immunology (Baltimore, Md. : 1950). 165(10): 5780-7. PMID: 11067937

Appearance :
Lyophilized
Physical State :
Solid
Solubility :
Soluble in water (1 mg/ml), and 0.5% TEA (1 mg/ml). Warming to 37°C with intermittent vortexing or sonication may be required to achieve complete solubilization in H2O.
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
UX2990000

Download SDS (MSDS)

Certificate of Analysis

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