Lincomycin A water soluble, broad spectrum antibiotic with activity against anaerobic bacteria and protozoans

Lincomycin (CAS 154-21-2)

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Synonym: Linocin; Lincolnensin; Jiemycin
Application: A water soluble, broad spectrum antibiotic with activity against anaerobic bacteria and protozoans
CAS Number: 154-21-2
Purity: ≥99%
Molecular Weight: 406.54
Molecular Formula: C18H34N2O6S
* Refer to Certificate of Analysis for lot specific data (including water content).
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Lincomycin is a polar, water soluble, broad spectrum antibiotic first isolated from Streptomyces licolnensis by researchers at Upjohn in 1962. Lincomycin was the first of a unique structural class, the lincosamides, containing a rare amino acid, 4-propyl-N- methylproline, coupled to an equally rare aminomethylthio- octopyranoside sugar. Lincomycin and semi-synthetic analogues are often incorrectly considered to be aminoglycosides but share little or no structural similarity. Lincomycin is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Lincomycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Lincomycin has been extensively studied with over 7,000 literature citations.

Physical State :
Solid
Derived From :
Streptomyces sp.
Solubility :
Soluble in ethanol, methanol, DMF, DMSO, and water.
Storage :
Store at -20° C
Melting Point :
262.24° C (Predicted)
Boiling Point :
~646.8° C at 760 mmHg (Predicted)
Density :
~1.3 g/cm3 (Predicted)
Refractive Index :
n20D 1.58 (Predicted)
pK Values :
pKa: 12.91 (Predicted), pKb: 8.78 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
RH6314000
PubChem CID :
3000540
MDL Number :
MFCD00135816
EC Number :
205-824-6
Beilstein Registry :
0707677
SMILES :
CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@@H](C)O

Download SDS (MSDS)

Certificate of Analysis

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