LG 100268A potent agonist of RXR

LG 100268 (CAS 153559-76-3)

LG 100268 | CAS 153559-76-3 is rated 5.0 out of 5 by 1.
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Application: A potent agonist of RXR
CAS Number: 153559-76-3
Molecular Weight: 363.49
Molecular Formula: C24H29NO2
* Refer to Certificate of Analysis for lot specific data (including water content).
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LG 100268 is a potent RXR agonist.


References

Clyne, C., et al.: J. Biol. Chem., 277, 20591 (2002), Santen, R., et al.: J. Clin. Endocrinol. Metab., 87, 3007 (2002), Falender, A., et al.: Endocrinology, 144, 3598 (2003), Sablin, E., et al.: Mol. Cell., 11, 1575 (2003)

Physical State :
Solid
Solubility :
Soluble in Chloroform and Methanol
Storage :
Store at -20° C
Melting Point :
275-277°C (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
3922
SMILES :
CC1=C(C=C2C(=C1)C(CCC2(C)C)(C)C)C3(CC3)C4=NC=C(C=C4)C(=O)O

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Certificate of Analysis

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LG 100268  Product Citations

See how others have used LG 100268. Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 24942043  Galvan, MD. et al. 2014. J Innate Immun. 6: 780-92.

PMID: # 23582768  Luu, W. et al. 2013. Atherosclerosis. 228: 362-9.

Citations 1 to 2 of 2 total
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Rated 5 out of 5 by from Mazumdar Mazumdar, A. et al. (PubMed 22926341) reported that the combination of tamoxifen and the rexinoid LG 100268 prevents ER-positive and ER-negative mammary tumors in p53-null mammary gland mice. -SCBT Publication Review
Date published: 2015-04-19
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