Leucinostatin AA broadly bioactive component produced by Paecilomyces lilacinus.

Leucinostatin A (CAS 76600-38-9)

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Synonym: Tryanocidin; Paecilotoxin A
Application: A broadly bioactive component produced by Paecilomyces lilacinus.
CAS Number: 76600-38-9
Purity: ≥95%
Molecular Weight: 1218.61
Molecular Formula: C62H111N11O13
* Refer to Certificate of Analysis for lot specific data (including water content).
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Leucinostatin A is the major component of an atypical nonapeptide complex produced by Paecilomyces lilacinus, first reported in 1973. Leucinostatins display broad bioactivity against Gram positive bacteria, fungi, plants and tumour cell lines. Leucinostatin A inhibits respiration by uncoupling oxidative phosphorylation and is potentiated by inhibitors such as venturicidin and oligomycin. More recently, interest in leucinostatin has focused on understanding its activity as an insulin-like growth factor I regulator, an ionophore, inhibitor of cell surface expression of viral glycoproteins and its anti- trypanosomal activity.

Physical State :
Solid
Derived From :
Paecilomyces sp.
Solubility :
Soluble in ethanol, methanol, DMF, DMSO, and water (limitedly).
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5477807
SMILES :
CCC(C)/C=C/C(=O)N1CC(CC1C(=O)NC(CC(C)CC(CC(=O)CC)O)C(=O)NC(C(C(C)C)O)C(=O)NC(C)(C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NCCC(=O)NC(C)CN(C)C)C

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Certificate of Analysis

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Necesito saber hay a que temperatura y durante cuanto tiempo es posible conservar la leucinostatina A una vez disuelta en 95% Metanol. Gracias

Asked by: BelenFBIO
Thank you very much for this question. We recommend to store the solid Leucinostatin A (CAS 76600-38-9) at -20°C. After dissolving this chemical in 95% Methanol, we suggest to keep the dissolved substance at the same conditions as the solid form and quickly use it up once it has been transferred into solution. This is the best option for long-term storage. Since we do not keep this chemical in solution we have not tested the stability of the dissolved compound.
Answered by: Technical Support Europe
Date published: 2017-12-15

At which temperatura and how long is leucinostatin A stable after to be disolved in 95% Methanol? Thank you

Asked by: BelenFBIO
Thank you very much for this question. We recommend to store the solid Leucinostatin A (CAS 76600-38-9) at -20°C. After dissolving this chemical in 95% Methanol, we suggest to keep the dissolved substance at the same conditions as the solid form and quickly use it up once it has been transferred into solution. This is the best option for long-term storage. Since we do not keep this chemical in solution we have not tested the stability of the dissolved compound.
Answered by: Technical Support Europe
Date published: 2017-12-15

What is the shipping temperature for this product?

Asked by: hawkeye11
This chemical, Leucinostatin A (CAS 76600-38-9), ships ambient.
Answered by: Chemical Support 1
Date published: 2017-03-06
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