L-Ascorbic acid, free acid Also known as vitamin C

L-Ascorbic acid, free acid (CAS 50-81-7)

L-Ascorbic acid, free acid | CAS 50-81-7 is rated 5.0 out of 5 by 1.
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Synonym: Vitamin C
Application: Also known as vitamin C
CAS Number: 50-81-7
Purity: ≥98%
Molecular Weight: 176.12
Molecular Formula: C6H8O6
* Refer to Certificate of Analysis for lot specific data (including water content).
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L-Ascorbic Acid, Free Acid protects cells against the damaging effects of radiation and oxygen radicals. L-Ascorbic Acid increases the rate of mineralization in osteoblasts, is involved in hydroxylation of proline and lysine, reduces Na+/Ca2+ exchange in cultured astrocytes and modulates cyclic nucleotide levels in B and T cells inhibits apoptosis in cultured rat ovarian follicles. Shown to inhibit T-type Ca++ CP α 1H.

Physical State :
Solid
Solubility :
Soluble in water (333 g/l) at 20° C, methanol, and DMSO.
Storage :
Store at room temperature
Melting Point :
191° C (dec.)
Boiling Point :
~415.83° C at 760 mmHg (Predicted)
Density :
1.65 g/cm3
Refractive Index :
n20D 1.71 (Predicted)
Optical Activity :
α20/D +20.5°±21.5°, c = 10 in water
IC50 :
Cav3.2 channels: IC50 = 6.5 µM (HEK 293 cells)
pK Values :
pKa: 4.5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
CI7650000
PubChem CID :
54670067
Merck Index :
14: 830
MDL Number :
MFCD00064328
EC Number :
200-066-2
Beilstein Registry :
84272
SMILES :
C([C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O

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Certificate of Analysis

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L-Ascorbic acid, free acid  Product Citations

See how others have used L-Ascorbic acid, free acid. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 22261727  Rani, MP. et al. 2012. J. Sci. Food Agric. 92: 1948-55.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Kim Kim, SR. et al. (PubMed 25896849) reported that L-Ascorbic acid reduces HMGB1 secretion in lipopolysaccharide-activated RAW 264.7 cells and improves survival rate in septic mice by activation of Nrf2/HO-1 signals. -SCBT Publication Review
Date published: 2015-03-31
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