L-α-Lysophosphatidylcholine (from egg yolk)A major component of oxidized low density lipoproteins that has been implicated in various inflammatory reactions

L-α-Lysophosphatidylcholine (from egg yolk) (CAS 9008-30-4)

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Synonym: 1-Acyl-sn-glycero-3-phosphocholine; L-α-Lysolecithin
Application: A major component of oxidized low density lipoproteins that has been implicated in various inflammatory reactions
CAS Number: 9008-30-4
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Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels.

Physical State :
Solid
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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