L-692,585 is a potent, non-peptidyl growth hormone receptor (GHS-R1a) agonist with a Ki value of 0.8 nM. L-692,585 increases the plasma growth hormone levels in vivo and is 2- to 2.5-fold more potent than GHRP-6.
1. Jacks, T., et al. 1994. J. Endocrinol. 143: 399-406. 2. Smith, R.G., et al. 1997. Endocr. Rev. 18: 621-645. 3. Glavaski-Joksimovic, A., et al. 2002. J. Endocrinol. 175: 625-636.
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