KLF15 (N-16) will be discontinued December 31, 2016; to receive a 10 µg sample of KLF15 (A-5): sc-271675, our highly recommended and much superior monoclonal antibody alternative to this product, please contact Technical Service.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
KLF15, KLF6 and KLF3 are Krüppel-like zinc finger-containing transcription factors. KLF15, a kidney-enriched Krüppel-like factor, is a transcriptonal activator that binds the CLCNKA promoter. KLF6 (also designated Zf9 or CPBP, for core promoter-binding protein) is rapidly induced during hepatic stellate cell activation and transactivates a reporter gene driven by the Collagen I promoter, suggesting that KLF6 plays a role in the response to tissue injury. KLF3 may play a role in hematopoiesis. KLF15, which is a nuclear protein, is expressed primarily in liver, heart, skeletal muscle and kidney tissues but is not detected in lymphoid tissues or bone marrow. It is an important regulator of GLUT4 in both adipose and muscle tissues.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PMID: # 22569180 Cheng, M. et al. 2012. Molecular characterization and transcriptional analysis of fad24 in pigs. Gene. 503: 208-214.
PMID: # 19720047 Horie, T. et al. 2009. MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes. Biochem. Biophys. Res. Commun.. 389: 315-320.
PMID: # 19293335 Yoshikawa, N. et al. 2009. Ligand-based gene expression profiling reveals novel roles of glucocorticoid receptor in cardiac metabolism. Am. J. Physiol. Endocrinol. Metab.. 296: E1363-E1373.
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