Kanamycin B sulfate Kanamycin B is an aminoglycoside with antibiotic properties that associates with bacterial ribosomal RNA. It is highly potent against gram-negative bacteria.

Kanamycin B sulfate  (CAS 29701-07-3)

Kanamycin B sulfate is rated 5.0 out of 5 by 1.
  • 2016-09-28T11:19CST
  • bvseo_cps, prod_bvrr, vn_cps_3.4.0
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202680, PRD, sort_relevancy
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 118ms
  • REVIEWS, PRODUCT
Synonym: Bekanamycinsulfate salt
Application: Highly potent antibiotic against Gram-negative bacteria often used in cell culture
CAS Number: 29701-07-3
Purity: ≥95%
Molecular Weight: 581.59
Molecular Formula: C18H37N5O10•H2SO4
* Refer to Certificate of Analysis for lot specific data (including water content).
submit a review for this product and receive 15 cruzcredits

Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
Kanamycin B sulfate sc-202680 250 mg $55.00

Kanamycin B is an aminoglycoside with antibiotic properties that associates with bacterial ribosomal RNA. The compound is highly potent against gram-negative bacteria. Other members of the aminoglycoside group include Kanamycin A (sc-205358) and Amikacin (sc-202457). Kanamycin B has five amino groups and has a stronger association with acidic phospholipids in comparison to Kanamycin A. Studies have shown that the Kcat value of the kanamycin group is higher compared to the neomycin group.


References

1. Basak, K. and Majumdar, S.K. 1973. Antimicrob. Agents Chemother. 4: 6-10. PMID: 4791483
2. Yung, M.W. and Green, C. 1987. J. Antibiot. 40: 862-867. PMID: 3610836
3. Carrier, D., et al. 1997. Biochem. Pharmacol. 53: 401-408. PMID: 9065744
4. Kwon, M., et al. 2001. Mol. Cells. 11: 303-311. PMID: 11459219
5. Norris, A.L., et al. 2010. Biochemistry. 49: 4027-4035. PMID: 20387903

Appearance :
Crystalline powder
Physical State :
Solid
Derived From :
Streptomyces kanamyceticus
Solubility :
Soluble in water (50 mg/ml), and aqueous solution (92.3 mg/ml).
Storage :
Store at -20° C
Boiling Point :
807.7° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.67 (Predicted)
IC50 :
Bacillus subtilis: IC50 = 0.39 ug.mL-1; Staphylococcus aureus: IC50 = 1.56 ug.mL-1; Mycobacterium tuberculosis: IC50 = 2.5 ug.mL-1; Escherichia coli: IC50 = 3.13 ug.mL-1; Pseudomonas aeruginosa: IC50 = 3.13 ug.mL-1
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
WK1976500
PubChem CID :
169075
Merck Index :
14: 5281
EC Number :
225-170-5
SMILES :
C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N.[O-]S(=O)(=O)[O-]

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

You May Also Like

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 41ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Shrestha Shrestha, S. et al. (PubMed 24040088) used Kanamycin B as a control against a structurally similar aminoglycoside, FG08. FG08 did not show anti-bacterial activity that was comparable to Kanamycin B. -SCBT Publication Review
Date published: 2015-03-02
  • 2016-09-28T11:19CST
  • bvseo_cps, prod_bvrr, vn_cps_3.4.0
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202680, PRD, sort_relevancy
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 37ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2016 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.