Ivermectin aglycone is a semi-synthetic produced by the hydrolysis of the disaccharide unit of ivermectin. This product is shown to be a potent inhibitor of nematode larval development but is devoid of paralytic activity. The aglycone has been shown to be used as a sensitive probe for the detection of some types of ivermectin resistance.
1. Chabala, J.C., et al. 1980. J. Med. Chem. 23: 1134-1136. PMID: 6893469
2. Gill, J.H., et al. 1991. Int. J. Parasitol. 21: 771-776. PMID: 1774112
See how others have used Ivermectin aglycone. Click on the entry to view the PubMed entry .
PMID: # 12458832 Sheriff, JC. et al. 2002. Parasitology. 125: 477-484.
PMID: # 9645874 Kotze, AC. et al. 1998. J. Parasitol. 84: 631-635.
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