Isobavachalcone An inhibitor of platelet aggregation

Isobavachalcone (CAS 20784-50-3)

Isobavachalcone | CAS 20784-50-3 is rated 5.0 out of 5 by 1.
  • y_2019, m_4, d_22, h_2
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.12
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202666, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 100ms
  • REVIEWS, PRODUCT
Synonym: 2',4',4-Trihydroxy-3'-[3''-methylbut-3''-enyl]chalcone
Application: An inhibitor of platelet aggregation
CAS Number: 20784-50-3
Purity: ≥97%
Molecular Weight: 324.40
Molecular Formula: C20H20O4
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Isobavachalcone inhibits platelet aggregation. Inhibitor of Epstein-Barr virus early antigen (EBV-EA) induction. Isobavachalcone exhibits potent inhibitory effect on skin tumor promotion. Potent inhibitor of MMP-2. Displays DNA strand-scission (cleaving) activity. Isobavachalcone hows antifungal activity.


References

1. Tsai, W.J., et al. 1996. J. Nat. Prod. 59: 671-672. PMID: 8759164
2. Haraguchi, H., et al. 2002. Phytother. Res. 16: 539-544. PMID: 12237811
3. Akihisa, T., et al. 2003. Cancer Lett. 201: 133-137. PMID: 14607326
4. Omisore, N.O., et al. 2005. Braz. J. Med. Biol. Res. 38: 1087-1094. PMID: 16007280
5. Akihisa, T., et al. 2006. J. Nat. Prod. 69: 38-42. PMID: 16441065

Appearance :
Oil
Physical State :
Liquid
Derived From :
Psoralea corylifolia.
Solubility :
Soluble in DMSO, and 100% ethanol..
Storage :
Store at -20° C
Melting Point :
210.09° C (Predicted)
Boiling Point :
~549.03° C at 760 mmHg (Predicted)
Density :
~1.2 g/mL (Predicted)
Refractive Index :
n20D 1.66 (Predicted)
IC50 :
Candida albicans: IC50 = 2 ug.mL-1; Filobasidiella neoformans: IC50 = 7 ug.mL-1 (cryptococcus neoformans); Vero: IC50 = 31.25 ug.mL-1 (chlorocebus aethiops); CYP19: IC50 >40 ug.mL-1 (human)
pK Values :
pKa: 7.99 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5281255
MDL Number :
MFCD00902090
SMILES :
CC(=CCC1=C(C=CC(=C1O)C(=O)/C=C/C2=CC=C(C=C2)O)O)C

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Isobavachalcone  Product Citations

See how others have used Isobavachalcone. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25704611  Lee, KM. et al. 2015. Eur. J. Pharmacol. 754: 11-8.

Citations 1 to 1 of 1 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 79ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Akihisa et al Akihisa et al. (PubMed ID 16441065) found that Isobavachalcone inhibited skin tumor growth in mice. -SCBT Publication Review
Date published: 2015-01-17
  • y_2019, m_4, d_22, h_2
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.12
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202666, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 222ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.