INDO 1/AM is a cell-permeable ester derivative of INDO 1. After crossing the cell membrane, INDO 1/AM is rapidly hydrolyzed by cytoplasmic esterases and remains trapped within the cell. INDO 1/AM has been used to selectively monitor Ca2+ levels in mitochondria and in the cytosol.
1. Lopez, M., et al. 1989. Cytometry. 10: 165-173. PMID: 2540938 2. Grierson, J.P., et al. 1992. J. Neurophysiol. 67: 704-714. PMID: 1315847 3. Griffiths, E.J., et al. 1997. Am. J. Physiol. 273: C37-C44. PMID: 9252440 4. Zhou, Z., et al. 1998. J. Physiol. 507: 379-403. PMID: 9518700
Soluble in acetonitrile (10 mg/ml), and DMSO.
Store at -20° C
1009.2° C at 760 mmHg (Predicted)
1.38 g/cm3 (Predicted)
n20D 1.58 (Predicted)
λex 330 nm, λem 450 nm in with Calcium; λex 356 nm, λem 478 nm in methanol
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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