GW1929 A high-affinity agonist of PPARγ

GW1929 (CAS 196808-24-9)

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Synonym: N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine
Application: A high-affinity agonist of PPARγ
CAS Number: 196808-24-9
Purity: ≥98%
Molecular Weight: 495.57
Molecular Formula: C30H29N3O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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GW1929 is a high affinity agonist of PPAR-γ.


References

1. Brown, K.K., et al, 1999. Diabetes. 90: 1415-1424. PMID: 10389847
2. Way, J.M., et al. 2001. J. Biol. Chem. 276: 25651-25653. PMID: 11373275

Physical State :
Solid
Solubility :
Soluble in DMSO (20 mg/mL).
Storage :
Store at room temperature
Refractive Index :
n20D 1.66
IC50 :
PPARγ: EC5050 = 13 nM (mouse); PPARγ: EC5050 = 6.2 nM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
16219422
MDL Number :
MFCD11045925
SMILES :
CN(CCOC1=CC=C(C=C1)CC(C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4.O

Download SDS (MSDS)

Certificate of Analysis

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