Guanosine-3prime,5prime-cyclic Monophosphate, 8-(2-Aminophenylthio)-Sodium SaltA selective activator of cGMP-dependent PK-1a

Guanosine-3′,5′-cyclic Monophosphate, 8-(2-Aminophenylthio)-Sodium Salt (CAS 144509-87-5)

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Application: A selective activator of cGMP-dependent PK-1a
CAS Number: 144509-87-5
Purity: ≥98%
Molecular Weight: 490.4
Molecular Formula: C16H16N6O7PS Na
* Refer to Certificate of Analysis for lot specific data (including water content).
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Guanosine-3',5'-cyclic Monophosphate, 8-(2-Aminophenylthio)-Sodium Salt is an isozyme-selective activator of cGKI α(cGMP-dependent protein kinase 1α) that shows about 200-fold selectivity for the activation of PKG 1α (cGKIα) over PKG 1β (cGKIβ).


References

Teede, H., et al. 2001. Clin. Sci. (London) 100, 473. Shekhar, K.R., et al. 1992. Mol. Pharmacol. 42, 103.

Appearance :
Lyophilized
Physical State :
Solid
Solubility :
Soluble in water (1 mg/ml).
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
16760482
SMILES :
C1C2C(C(C(O2)N3C4=C(C(=O)N=C(N4)N)N=C3SC5=CC=CC=C5N)O)OP(=O)(O1)[O-].[Na+]

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Certificate of Analysis

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