Granzyme B inhibitor is a weak inhibitor of murine and human Granzyme B. It also inhibits the apoptosis-related DNA fragmentation in lymphocytes by fragmentin 2, which is a rat lymphocyte granule protease homologous to Granzyme B (ID50 = 300 nM).
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For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Asked by: liya
Gong, B., et al. 1999. Cell Growth Different. 10, 491.
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Thank you for your question. SC-3087 is an irreversible, cell-permeable inhibitor of granzyme B. Above are some references that may help.
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