Glycodeoxycholic acid sodium salt An activator of endonuclease-mediated apoptotis in hepatocytes

Glycodeoxycholic acid sodium salt (CAS 16409-34-0)

Glycodeoxycholic acid sodium salt | CAS 16409-34-0 is rated 5.0 out of 5 by 1.
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Synonym: Sodium glycodeoxycholate
Application: An activator of endonuclease-mediated apoptotis in hepatocytes
CAS Number: 16409-34-0
Purity: ≥96%
Molecular Weight: 471.61
Molecular Formula: C26H42NO5•Na
* Refer to Certificate of Analysis for lot specific data (including water content).
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Glycodeoxycholic Acid, Sodium Salt induces apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases.


References

1. Kwo, P., et al., 1995. Nuclear serine protease activity contributes to bile acid-induced apoptosis in hepatocytes. The American journal of physiology. 268(4 Pt 1): G613-21. PMID: 7733287

Physical State :
Solid
Solubility :
Soluble in water (10 mg/ml).
Storage :
Store at room temperature
Boiling Point :
655.6° C at 760 mmHg
Refractive Index :
n20D ~1.55
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
MB9670000
PubChem CID :
16760472
MDL Number :
MFCD00036742
EC Number :
240-455-4
SMILES :
CC(CCC(=O)NCC(=O)[O-])C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C.[Na+]

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Certificate of Analysis

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Rated 5 out of 5 by from Erb s H; et al Erb s H; et al. (PubMed ID: 26376346) utilized Glycodeoxycholic acid sodium salt to develop acute necrotizing pancreatitis in rats. -SCBT Publication Review
Date published: 2015-02-23
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