Glycochenodeoxycholic acid, sodium salt A bile acid shown to induce apoptosis in isolated hepatocytes

Glycochenodeoxycholic acid, sodium salt (CAS 16564-43-5)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 77ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: Sodium glycochenodeoxycholate; 3α,7α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide sodium salt
Application: A bile acid shown to induce apoptosis in isolated hepatocytes
CAS Number: 16564-43-5
Purity: ≥97%
Molecular Weight: 471.61
Molecular Formula: C26H42NNaO5
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Glycochenodeoxycholic acid, sodium salt is a bile acid that functions to solubilise fats for digestive absorption. This compound has been shown to inhibit calcium phosphate precipitation by preventing the formation of amorphous calcium phosphate to calcium hydroxyapatite. This product has also been shown to induce apoptosis in isolated hepatocytes via modulation of PKC activity.


References

1. Barnes, S., et al. 1979. J. Lipid Res. 20: 952-959. PMID: 533830
2. Penagini, R., et al. 1989. Gut. 30: 609-617. PMID: 2731753
3. Qiu, S.M., et al. 1991. J. Clin. Invest. 88: 1265-1271. PMID: 1655828
4. Gonzalez, B., et al. 2000. Mol. Cell. Biochem. 207: 19-27. PMID: 10888222
5. Iwata, M., et al. 2003. Hepatol. Res. 25: 329-342. PMID: 12697255
6. Utanohara, S., et al. 2005. Toxicology. 214: 77-86. PMID: 16023280

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (50 mg/ml), DMSO, and methanol.
Storage :
Store at 4° C
Melting Point :
196-198° C
Refractive Index :
n20D ~1.55 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
23696298
MDL Number :
MFCD00036743
Beilstein Registry :
3847290
SMILES :
C[C@H](CCC(=O)NCC(=O)[O-])[C@H]1CC[C@@H]2[C@@]1(CCC3[C@H]2[C@@H](C[C@H]4C3(CC[C@H](C4)O)C)O)C.[Na+]

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Glycochenodeoxycholic acid, sodium salt  Product Citations

See how others have used Glycochenodeoxycholic acid, sodium salt. Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 24448653  Jia, X. et al. 2014. Digestive diseases and sciences. 59: 1490-501.

PMID: # 23544269  Suzuki, Y. et al. 2013. Nagoya journal of medical science. 75: 57-71.

Citations 1 to 2 of 2 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 106ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 34ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.