Glyco-SNAP-1 is a water-soluble nitric oxide (NO) donor. It is more stable than SNAP (sc-200319) in aqueous solution with or without EDTA, and is relatively stable at a high pH (pH 8 - 9). The SNAP moiety acts as an NO group donor and the sugar moiety provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes at a much slower rate in the presence of thiols such as glutathione or cysteine.
1. Hou, Y., et al., 1999. Glyco-S-nitrosothiols: sugar-SNAP, a new type of nitric oxide donor. Methods in enzymology. 301(): 242-9. PMID: 9919573
2. Wu, Jun., et al., 2005. Acid sphingomyelinase is induced by butyrate but does not initiate the anticancer effect of butyrate in HT29 and HepG2 cells. Journal of lipid research. 46(9): 1944-52. PMID: 15961787
3. Ohsugi, Shuji., et al., 2007. An inhaled inducible nitric oxide synthase inhibitor reduces damage of Candida-induced acute lung injury. Biomedical research (Tokyo, Japan). 28(2): 91-9. PMID: 17510494
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.