Glyco-SNAP-1A water-soluble nitric oxide donor

Glyco-SNAP-1 (CAS 188849-81-2)

Glyco-SNAP-1 | CAS 188849-81-2 is rated 5.0 out of 5 by 1.
  • y_2019, m_8, d_22, h_22
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.13
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_221680, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 135ms
  • REVIEWS, PRODUCT
Synonym: N-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide
Application: A water-soluble nitric oxide donor
CAS Number: 188849-81-2
Purity: ≥96%
Molecular Weight: 381.40
Molecular Formula: C13H23N3O8S
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Glyco-SNAP-1 is a water-soluble nitric oxide (NO) donor. It is more stable than SNAP (sc-200319) in aqueous solution with or without EDTA, and is relatively stable at a high pH (pH 8 - 9). The SNAP moiety acts as an NO group donor and the sugar moiety provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes at a much slower rate in the presence of thiols such as glutathione or cysteine.


References

1. Hou, Y., et al., 1999. Glyco-S-nitrosothiols: sugar-SNAP, a new type of nitric oxide donor. Methods in enzymology. 301(): 242-9. PMID: 9919573
2. Wu, Jun., et al., 2005. Acid sphingomyelinase is induced by butyrate but does not initiate the anticancer effect of butyrate in HT29 and HepG2 cells. Journal of lipid research. 46(9): 1944-52. PMID: 15961787
3. Ohsugi, Shuji., et al., 2007. An inhaled inducible nitric oxide synthase inhibitor reduces damage of Candida-induced acute lung injury. Biomedical research (Tokyo, Japan). 28(2): 91-9. PMID: 17510494

Physical State :
Solid
Solubility :
Soluble in water (100 mg/ml), aqueous buffers (100 mg/ml), and methanol (5 mg/ml).
Storage :
Store at -20° C
Melting Point :
280.44° C (Predicted)
Boiling Point :
645.23° C (Predicted)
Density :
1.64 g/cm3 (Predicted)
Refractive Index :
n20D 1.65 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
10385174
MDL Number :
MFCD01074980
SMILES :
CC(=O)NC(C(=O)N[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C(C)(C)SN=O

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 112ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Various publications cite the use of Glyco Various publications cite the use of Glyco-SNAP-1 as a nitric oxide donor. -SCBT Publication Review
Date published: 2015-01-06
  • y_2019, m_8, d_22, h_22
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.13
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_221680, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 47ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.