Glutaraldehyde solution, 70% w/w, may be used as a fixative for electron microscopy. In the laboratory, glutaraldehyde solution is commonly used as an amine-reactive homobifunctional crosslinker and as a disinfectant for medical equipment. Glutaraldehyde may effectively crosslink amine and hydrazine derivatives to proteins and other amine-containing polymers; biotin hydrazides have been directly coupled to nucleic acids with glutaraldehyde in a reaction that is potentially useful for conjugating fluorescent hydrazides and hydroxylamines to DNA.
1. Delcros, J.G., et al. 1995. J. Immunol. Methods. 185: 191-198. PMID: 7561129
2. Vuolanto, A., et al. 2004. Biotechnol. Prog. 20: 771-776. PMID: 15176881
3. Guo, J.B., et al. 2010. Anal. Chim. Acta. 658: 197-203. PMID: 20103095
4. Sai, N., et al. 2010. Talanta. 82: 1113-1121. PMID: 20801306
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.