Glutaraldehyde solution, 25% w/w

Glutaraldehyde solution, 25% w/w (CAS 111-30-8)

Glutaraldehyde solution, 25% w/w | CAS 111-30-8 is rated 5.0 out of 5 by 1.
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Synonym: Pentane-1,5-dial; Glutaral; Glutaric dialdehyde
Application: A protein cross-linking agent
CAS Number: 111-30-8
Molecular Weight: 100.12
Molecular Formula: C5H8O2
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Glutaraldehyde solution, 25% in water, is primarily for use as a protein cross-linking agent. This grade is not recommended for use as an electron microscopy fixative. In the laboratory, glutaraldehyde solution is commonly used as an amine-reactive homobifunctional crosslinker and as a disinfectant for medical equipment. Glutaraldehyde may effectively crosslink amine and hydrazine derivatives to proteins and other amine-containing polymers; biotin hydrazides have been directly coupled to nucleic acids with glutaraldehyde in a reaction that is potentially useful for conjugating fluorescent hydrazides and hydroxylamines to DNA.


References

1. Delcros, J.G., et al. 1995. J. Immunol. Methods. 185: 191-198. PMID: 7561129
2. Vuolanto, A., et al. 2004. Biotechnol. Prog. 20: 771-776. PMID: 15176881
3. Guo, J.B., et al. 2010. Anal. Chim. Acta. 658: 197-203. PMID: 20103095
4. Sai, N., et al. 2010. Talanta. 82: 1113-1121. PMID: 20801306

Usage :
This grade is not recommended for use as an electron microscopy fixative. For electron microscopy grade, please see sc-257558.
Formulation :
25% in water
Physical State :
Liquid
Solubility :
Soluble in water, ethanol, benzene, and ether.
Storage :
Store at -20° C
Melting Point :
-10° C
Boiling Point :
101° C at 760 mmHg
Density :
1.06 g/mL at 20° C
Refractive Index :
n20D 1.37
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
MA2450000
Transport :
UN 2922, Class 8(6.1), Packing group III
PubChem CID :
3485
Merck Index :
14: 4472
MDL Number :
MFCD00007025
EC Number :
203-856-5
Beilstein Registry :
605390
SMILES :
C(CC=O)CC=O

Download SDS (MSDS)

Certificate of Analysis

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Does this glutaraldehyde solution meet the stadards of USP 41?

Asked by: Daniel98498498
Thank you for your question. All Santa Cruz Biotechnology, Inc. reagents are manufactured for in-vitro laboratory use only (RUO). They must not be used in medical diagnostics and they are not to be administered to humans or animals. They do not meet the requirements of any medical standards.
Answered by: SCBT Heidelberg Support
Date published: 2019-01-06
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Rated 5 out of 5 by from Various publications cite the use of Glutaraldehyde Various publications cite the use of Glutaraldehyde solution (Pentane-1,5-dial; Glutaral; Glutaric dialdehyde), as an amine-reactive homobifunctional crosslinker and as a disinfectant for medical equipment. Glutaraldehyde may effectively crosslink amine and hydrazine derivatives to proteins and other amine-containing polymers; biotin hydrazides have been directly coupled to nucleic acids with glutaraldehyde in a reaction that is potentially useful for conjugating fluorescent hydrazides and hydroxylamines to DNA. This grade is not recommended for use as an electron microscopy fixative. For electron microscopy grade, please see sc-257558. -SCBT Publication Review
Date published: 2015-03-09
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