Gentamicin Sulfate, 500X Solution A protein synthesis inhibiting antibiotic

Gentamicin Sulfate, 500X Solution (CAS 1405-41-0)

Gentamicin Sulfate, 500X Solution | CAS 1405-41-0 is rated 5.0 out of 5 by 1.
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Application: A protein synthesis inhibiting antibiotic
CAS Number: 1405-41-0
Molecular Weight: 575.67
Molecular Formula: C21H43N5O7 H2SO4
* Refer to Certificate of Analysis for lot specific data (including water content).
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Gentamicin Sulfate, 500X Solution is an aminoglycoside antibiotic which acts by both inhibiting protein synthesis in susceptible bacteria and binding to the surface of gram-negative bacterial cells. The cell binding activity is believed to disrupt the packing of lipopolysacchardes of the outer membrane leading to hole formation and cell lysis. Gentamicin Sulfate, 500X Solution is active against many strains of gram-negative bacteria, Pseudomonas aeruginosa, the gram-positive Staphylococcus aeruginosa as well as some strains of Mycobacterium tuberculosis. Activity: >600 I.U./mg Recommended working concentration: 100 μg/ml; 500X


References

1. Kadurugamuwa, J.L., et al. 1993. Antimicrob. Agents Chemother. 37: 715-721. PMID: 8494366
2. Kadurugamuwa, J.L., et al. 1993. J. Bacteriol. 175: 5798-5805. PMID: 8376327

Usage :
Recommended working concentration: 100 µg/ml
Formulation :
50 mg/ml in DI water
Physical State :
Liquid
Solubility :
Soluble in water. almost Insoluble in ethanol, and ether.
Storage :
Store at 4° C
Optical Activity :
α20/D +117°, c = 10 in water
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
PubChem CID :
44134730
Merck Index :
14: 4392
MDL Number :
MFCD00270181
EC Number :
215-778-9
SMILES :
CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC.OS(=O)(=O)O

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Certificate of Analysis

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Gentamicin Sulfate, 500X Solution  Product Citations

See how others have used Gentamicin Sulfate, 500X Solution. Click on the entry to view the PubMed entry .

Citations 1 to 10 of 11 total

PMID: # 16099860  Li, G. et al. 2005. Endocrinology. 146: 4690-4696.

PMID: # 14742295  Tourkina, E. et al. 2004. Am. J. Respir. Cell Mol. Biol. 31: 28-35.

PMID: # 15472120  Li, L. et al. 2004. Circ. Res. 95: 877-883.

PMID: # 12829655  Li, L. et al. 2003. Diabetes. 52: 1843-1850.

PMID: # 11375350  Nakagami, H. et al. 2001. Diabetes. 50: 1472-1481.

PMID: # 11408253  Ray, RM. et al. 2001. Am. J. Physiol. Gastrointest. Liver Physiol. 281: G37-G43.

PMID: # 11579091  Bogatkevich, G.S. et al. 2001. J. Biol. Chem. 276: 45184-45192.

PMID: # 10804206  Glazner, GW. et al. 2000. J. Neurosci. 20: 3641-3649.

PMID: # 9950818  Patel, AR. et al. 1999. Am. J. Physiol. 276: G441-G450.

PMID: # 9499057  Fortunato, EA. et al. 1998. J. Virol. 72: 2033-2039.

Citations 1 to 10 of 11 total
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Rated 5 out of 5 by from Various publications cite the use of gentamicin Various publications cite the use of gentamicin sulfate as an antibiotic in media. -SCBT Publication Review
Date published: 2015-05-04
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