Furazolidone A nitrofuran derivative with antiprotozoal and antibacterial activity

Furazolidone (CAS 67-45-8)

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Synonym: 3-[[(5-Nitro-2-furanyl)methylene]amino]-2-oxazolidinone; 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidinone; Diafuron; Furaxon; Furazol; Furazolidon; Giardil; Giarlam; Medaron; Ortazol; Puradin; Roptazol; Tikofuran; Topazone; Trifurox
Application: A nitrofuran derivative with antiprotozoal and antibacterial activity
CAS Number: 67-45-8
Molecular Weight: 225.16
Molecular Formula: C8H7N3O5
* Refer to Certificate of Analysis for lot specific data (including water content).
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Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. It is also an inhibitor of MAO.


References

Yurchenco, J.A., et al.: Antimicrob. Chemother., 3, 1035 (1953), Sharma, C., et al.: J. Clin. Microbiol., 36, 756 (1998),

Physical State :
Solid
Solubility :
Soluble in formic acid (50 mg/ml), DMSO, DMF, and hot pyridine. Insoluble in water.
Storage :
Store at -20° C
Melting Point :
254-256° C (lit.)(dec.)
Boiling Point :
342.56° C
Density :
1.6 g/cm3
Refractive Index :
n20D 1.72
IC50 :
Trypanosoma cruzi: EC5050 = 400 nM; ADMET: EC5050 >50 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
RQ3675000
PubChem CID :
5323714
Merck Index :
14: 4300
MDL Number :
MFCD00010550
EC Number :
200-653-3
Beilstein Registry :
8317414
SMILES :
C1COC(=O)N1/N=C/C2=CC=C(O2)[N+](=O)[O-]

Download SDS (MSDS)

Certificate of Analysis

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