Fosfomycin Calcium A bacterial wall synthesis inhibitor

Fosfomycin Calcium (CAS 26016-98-8)

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Synonym: Calcium phosphomycin; Fosmicin
Application: A bacterial wall synthesis inhibitor
CAS Number: 26016-98-8
Purity: ≥97%
Molecular Weight: 176.12
Molecular Formula: C3H5CaO4P
* Refer to Certificate of Analysis for lot specific data (including water content).
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Fosfomycin Calcium is the Ca2+ salt preparation of Fosfomycin, a phosphonic acid epoxide antibiotic. Fosfomycin is described to inhibit cell wall synthesis through inhibition of UDP-N-acetylglucosamine enolpyruvyl transferase, the enzyme responsible for catalysis of the first committed step in peptidoglycan biosynthesis.


References

1. Fujita, M., et al. 1975. Jpn J Antibiot. 28: 314-319. PMID: 1152285
2. Brown, E.D., et al. 1995. J. Bacteriol. 177: 4194-4197. PMID: 7608103
3. Krause, R., et al. 2001. J. Antimicrob. Chemother. 47: 141-146. PMID: 11157896

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in 1 M HCl (50 mg/ml).
Storage :
Store at 4° C
Boiling Point :
342.7° C at 760 mmHg (Predicted)
Refractive Index :
n20D ~1.49 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
RTECS :
SZ7895000
PubChem CID :
93095
Merck Index :
14: 4254
MDL Number :
MFCD00070095
EC Number :
247-408-7
SMILES :
C[C@H]1[C@H](O1)P(=O)([O-])[O-].[Ca+2]

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Fosfomycin Calcium  Product Citations

See how others have used Fosfomycin Calcium. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 1152285  Fujita, M. et al. 1975. Jpn J Antibiot. 28: 314-319.

Citations 1 to 1 of 1 total

Boa tarde. Essa fosfomicina é comercializada em pó? Qual é a forma de preparo? Obrigada

Asked by: Juliana Nardi Bortolança
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