Etoposide Phosphate is a derivative of Etoposide (VP-16) (sc-3512). Etoposide is a topoisomerase II inhibitor that is widely used as an apoptosis inducer. Etoposide exhibits antineoplastic and anti-mitotic properties. Inhibits DNA synthesis and induces double-strand and single-strand DNA breaks. Cell-cycle dependent and cell-cycle specific to late S and G2 phases. Activates p53 resulting in upregulated expression of TRAIL-R2 (DR5) and Bak to overcome TRAIL resistance in Bax-deficient human colon carcinoma cancer cells. Etoposide Phosphate is an activator of p53.
Soluble in cold water (easily).
Store at room temperature
~1.64 g/cm3 (Predicted)
n20D ~1.66 (Predicted)
Topoisomerase 2: IC50 = 59.2 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of
Many articles reported Etoposide PhosphateMany articles reported Etoposide Phosphate, a derivative of etoposide, to be a topoisomeras II inhibitor, and induce apoptosis in some cancers. -SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.