Ethambutol An antitubercular antibiotic

Ethambutol (CAS 74-55-5)

Ethambutol | CAS 74-55-5 is rated 5.0 out of 5 by 1.
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Synonym: Myambutol; Tibutol
Application: An antitubercular antibiotic
CAS Number: 74-55-5
Purity: ≥98%
Molecular Weight: 204.31
Molecular Formula: C10H24N2O2
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ethambutol is an antibacterial agent.


References

1. Bernard, E M., et al., 1993. Activities of antimicrobial agents against clinical isolates of Mycobacterium haemophilum. Antimicrobial agents and chemotherapy. 37(11): 2323-6. PMID: 8285613

Physical State :
Solid
Solubility :
Soluble in chloroform, methylene chloride, and water (sparingly soluble).
Storage :
Store at 4° C
Melting Point :
199-204° C
Boiling Point :
~345.3° C at 760 mmHg (Predicted)
Density :
~1.0 g/cm3 (Predicted)
Refractive Index :
n20D 1.48 (Predicted)
IC50 :
Mycobacterium smegmatis: IC50 = 3.2 µM; Mycobacterium tuberculosis H37Rv: IC50 = 4 ug.mL-1; Vero: IC50 = >62.5 ug.mL-1 (Chlorocebus aethiops)
pK Values :
pKb: 9.59 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
14052
MDL Number :
MFCD00242828
EC Number :
200-810-6
Beilstein Registry :
6312870
SMILES :
CC[C@@H](CO)NCCN[C@@H](CC)CO

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Cinici et al Cinici et al. (PubMed ID 26339826) used Ethambutol to induce retinal oxidative damage in tuberculosis patients in order to determine if hiamine pyrophosphate had a protective effect. -SCBT Publication Review
Date published: 2015-02-18
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