Eltoprazine hydrochlorideA partial agonist at SR-1 and SR-2C

Eltoprazine hydrochloride (CAS 98224-03-4)

Eltoprazine hydrochloride | CAS 98224-03-4 is rated 5.0 out of 5 by 1.
  • y_2019, m_8, d_22, h_20
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.13
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_203574, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 268ms
  • REVIEWS, PRODUCT
Synonym: 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine hydrochloride
Application: A partial agonist at SR-1 and SR-2C
CAS Number: 98224-03-4
Purity: ≥98%
Molecular Weight: 256.73
Molecular Formula: C12H16N2O2•xHCl
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Eltoprazine hydrochloride is a SR-1 and SR-2C receptor partial agonist (Ki values are 40, 52 and 81 nM for SR-1A, SR-1B and SR-2C, respectively). HCl content varies. Please refer to Certificate of Analysis for specific lot content.


References

1. Miczek, K.A., et al. 1989. Psychopharmacol. Bull. 25: 399-403.
2. Schipper, J., et al. 1990. Drug Metabol.Drug Interact. 8: 85-114.
3. Gommans, J., et al. 1997. Life Sci. 61: 11-19.

Physical State :
Solid
Solubility :
Soluble in water (100 mM).
Storage :
Store at 4° C
Melting Point :
250° C
Boiling Point :
384.3° C at 760 mmHg (Predicted)
Refractive Index :
n20D ~1.56 (Predicted)
Ki Data :
5-HT1A: Ki= 40 nM; 5-HT1B: Ki= 52 nM; 5-HT2C: Ki= 81 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
3025067
MDL Number :
MFCD06245586
SMILES :
C1CN(CCN1)C2=C3C(=CC=C2)OCCO3.Cl

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 166ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Paolone et al Paolone et al. (PubMed ID 26207892) found that Eltoprazine prevented dyskinesias induced by l-dopa by decreasing striatal glutamate and direct pathway activity. -SCBT Publication Review
Date published: 2015-04-14
  • y_2019, m_8, d_22, h_20
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.13
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_203574, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 24ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.