Eicosadienoic Acid (5Z,14Z)

Eicosadienoic Acid (5Z,14Z) (CAS 122055-58-7)

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Application: Inhibits inosine 5'-monophosphate
CAS Number: 122055-58-7
Molecular Weight: 308.5
Molecular Formula: C20H36O2
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* Refer to Certificate of Analysis for lot specific data (including water content).
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Eicosadienoic acid is a novel w-6 C20:2 fatty acid having a more common form (11Z,14Z) that competitively inhibits inosine 5′-monophosphate dehydrogenase1 and inhibits the binding of LTB4 to its receptor in neutrophils.2 There has been shown a negative correlation between serum levels of eicosadienoic acids and degrees of sleep disturbances.3 In vivo, eicosadienoic acis are converted by desaturases to eicosatrienoic acids, potent vasodilators. No studies have been conducted on the physiological effects of eicosadienoic acid.


References

1. Mizushina, Y., et al. 2007. Biochimie 89: 581-590. PMID: 17383068
2. Yagaloff, K.A., et al. 1995. Prostaglandins Leukot. Essent. Fatty Acids. 52: 293-297. PMID: 7630916
3. Irmisch, G., et al. 2007. Prostaglandins Leukot Essent Fatty Acids 76: 1-7. PMID: 17123808

Formulation :
A solution in ethanol
Appearance :
A solution in ethanol
Physical State :
Liquid
Storage :
Store at -20° C
Boiling Point :
78° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Transport :
UN 1170, Class 3, Packing group II
PubChem CID :
35028442
SMILES :
CCCCCC=CCCCCCCCC=CCCCC(=O)O

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Certificate of Analysis

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