Eicosa-11Z,14Z-dienoic Acid Eicosa-11Z,14Z-dienoic acid is a polyunsaturated lipid analog of arachidonic acid. It has been shown to inhibit calcineurin.

Eicosa-11Z,14Z-dienoic Acid  (CAS 2091-39-6)

Eicosa-11Z,14Z-dienoic Acid is rated 5.0 out of 5 by 1.
  • 2016-09-27T11:10CST
  • bvseo_cps, prod_bvrr, vn_cps_3.4.0
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_200776, PRD, sort_relevancy
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 568ms
  • REVIEWS, PRODUCT
| See 1 Citations
Synonym: cis-11,14-Eicosadienoic acid
Application: A polyunsaturated lipid analog of arachidonic acid that inhibits calcineurin
CAS Number: 2091-39-6
Molecular Weight: 308.50
Molecular Formula: C20H36O2
* Refer to Certificate of Analysis for lot specific data (including water content).
submit a review for this product and receive 15 cruzcredits

Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
Eicosa-11Z,14Z-dienoic Acid sc-200776 100 mg $30.00
Eicosa-11Z,14Z-dienoic Acid sc-200776A 1 g $159.00

Eicosa-11Z,14Z-dienoic acid is a polyunsaturated lipid analog of arachidonic acid. It has been shown to inhibit PP2 (calcineurin), a protein phosphatase which activates immune system T cells, to some extent in the absence of calmodulin.


References

1. Tokheim, A.M., et al. 2006. Bioorg. Chem. 34: 66-76. PMID: 16464485

Appearance :
Oil
Physical State :
Liquid
Solubility :
Soluble in ethanol (~100 mg/ml), DMSO (~100 mg/ml), and DMF (~100 mg/ml). Insoluble in water.
Storage :
Store at -20° C
Boiling Point :
198° C at 0.08 mmHg
Refractive Index :
n20D 1.48
Ki Data :
binding of [3H]-LTB4 to neutrophil membranes: Ki= 3 µM (pig)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
6439848
MDL Number :
MFCD00673431
SMILES :
CCCCC/C=CC/C=CCCCCCCCCCC(=O)O

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

You May Also Like

Eicosa-11Z,14Z-dienoic Acid Product Citations

See how others have used Eicosa-11Z,14Z-dienoic Acid. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 9108053
Cui, X.L. et al. 1997. Arachidonic acid activates c-jun N-terminal kinase through NADPH oxidase in rabbit proximal tubular epithelial cells. Proc. Natl. Acad. Sci. USA. 94: 3771-3776.

Citations 1 to 1 of 1 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 90ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Tokheim Tokheim, AM. et al. (PubMed 16464485) reported that Eicosa-11Z,14Z-dienoic Acid effectively inhibited calcineurin. -SCBT Publication Review
Date published: 2015-06-02
  • 2016-09-27T11:10CST
  • bvseo_cps, prod_bvrr, vn_cps_3.4.0
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_200776, PRD, sort_relevancy
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 6ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2016 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.