EDTA, 0.5 M, pH 8.0A sterile-filtered solution of 0.5 M EDTA in H2O treated with DEPC, for use in molecular biology apps

EDTA, 0.5 M, pH 8.0 (CAS 60-00-4)

EDTA, 0.5 M, pH 8.0 | CAS 60-00-4 is rated 5.0 out of 5 by 2.
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Synonym: Ethylenediaminetetraacetic Acid Sodium Salt Solution
Application: A sterile-filtered solution of 0.5 M EDTA in H2O treated with DEPC, for use in molecular biology apps
CAS Number: 60-00-4
Molecular Weight: 292.24
Molecular Formula: C10H16N2O8•xNa
* Refer to Certificate of Analysis for lot specific data (including water content).
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EDTA, 0.5 M, pH 8.0, is a sterile-filtered solution of 0.5 M EDTA in H2O treated with diethyl pyrocarbonate (DEPC). EDTA (Ethylenediaminetetraacetic acid) is a chelating agent, a general chemical, and a sequestrant. Suitable for use in molecular biology applications. EDTA is used extensively as chelator of divalent cations such as Ca2+. Useful in molecular biology applications to minimize metal ion contaminants. Also used to facilitate enzymatic reactions that could be inhibited by heavy metal traces. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.


References

1. Child, G.P. 1951. Science. 114: 466-467. PMID: 14892768
2. Friess, E.G., et al. 1954. Arch Biochem. 53: 311-313. PMID: 13208306
3. Sapeika, N. 1955. S. Afr. Med. J. 29: 137-139. PMID: 14358876
4. Sheppard, R.L., et al. 1997. Anal. Chem. 69: 477A-480A. PMID: 9253241
5. Lanigan, R.S. and Yamarik, T.A. 2002. Int. J. Toxicol. 21: 95-142. PMID: 12396676

Physical State :
Liquid
Solubility :
Soluble in water.
pH :
8.0
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
6049
Merck Index :
14: 3517
MDL Number :
MFCD00149685
Beilstein Registry :
3858591
SMILES :
C(CN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O

Download SDS (MSDS)

Certificate of Analysis

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EDTA, 0.5 M, pH 8.0  Product Citations

See how others have used EDTA, 0.5 M, pH 8.0. Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 22529697  Liang, YM. et al. 2012. World journal of gastroenterology. 18: 1664-71.

PMID: # 20363778  Argandoña, M. et al. 2010. Appl. Environ. Microbiol. 76: 3575-3589.

PMID: # 18338400  Le Pichon, CE. et al. 2008. J. Comp. Neurol. 508: 487-499.

Citations 1 to 3 of 3 total
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Rated 5 out of 5 by from lab manager I bought this product month ago and it is great ready to use product.
Date published: 2018-09-04
Rated 5 out of 5 by from Various publications cite the use of EDTA Various publications cite the use of EDTA as a highly efficient chelating agent of divalent cations. Suitable for use in biology applications by reducing metal ion contamination. -SCBT Publication Review
Date published: 2015-01-10
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