DPPH, Free Radical DPPH, Free Radical is a cell-permeable, stable free radical that is a hydrogen radical scavenger. Induces free-radical injury to tissues. Used in screens for detecting free radical scavenging activity of antioxidants.

DPPH, Free Radical  (CAS 1898-66-4)

DPPH, Free Radical is rated 5.0 out of 5 by 1.
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| See 1 Citations
Synonym: 1,1-Diphenyl-2-picrylhydrazyl radical; 2,2-Diphenyl-1-picrylhydrazyl (free radical)
Application: A sensitive colormetric free radical scavenger
CAS Number: 1898-66-4
Purity: ≥90%
Molecular Weight: 394.32
Molecular Formula: C18H12N5O6
* Refer to Certificate of Analysis for lot specific data (including water content).
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PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
DPPH, Free Radical sc-202591 50 mg $40.00

DPPH, Free Radical is a cell-permeable, stable free radical that acts as a hydrogen radical scavenger. Originally developed to detect melanin metabolites in the urine of subjects with malignant melanoma, it has found numerous applications as a general antioxidant detector. Useful in inducing free-radical injury to tissues and as a screening tool for detecting free radical scavenging activity of antioxidants. The ability of a compound to decolorize DPPH free radical signifies the reactivity of the tested compound. Used in the quantitative determination of aliphatic and aromatic thiols by indirect spectroscopy and for photometric determination of tocopherol.


References

1. Banda, P.W., et al. 1974. Anal. Chem. 46: 1772-1777. PMID: 4411963
2. Dinis, T.C., et al. 1994. Arch. Biochem. Biophys. 315: 161-169. PMID: 7979394
3. Ancerewicz, J., et al. 1998. Free Radic. Biol. Med. 25: 113-120. PMID: 9655529
4. Karki, S.B., et al. 2000. J Pharm Sci. 89: 1518-1524. PMID: 11042599
5. Weber, V., et al. 2001. Arzneimittelforschung. 51: 877-884. PMID: 11765588

Physical State :
Solid
Solubility :
Soluble in DMF, EtOH, chloroform, ether, carbon disulfinde, acetone, oils, carbon tetrachloride, glacial acetis acid, and toluene. Insoluble in water.
Storage :
Store at -20° C
Melting Point :
~135° C (lit.)(dec.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
PubChem CID :
2735032
Merck Index :
14: 3330
MDL Number :
MFCD00007231
EC Number :
217-591-8
Beilstein Registry :
1846081
SMILES :
C1=CC=C(C=C1)N(C2=CC=CC=C2)[N]C3=C(C=C(C=C3[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-]

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Certificate of Analysis

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Citations 1 to 1 of 1 total

PMID: # 11745031
Song, EK. et al. 2001. Diarylheptanoids with free radical scavenging and hepatoprotective activity in vitro from Curcuma longa. Planta Med.. 67: 876-877.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Various publications cite the numerous uses Various publications cite the numerous uses of DPPH as a general antioxidant detector. It is also useful in inducing free-radical injury to tissues and in the quantitative determination of aliphatic and aromatic thiols by indirect spectroscopy and for photometric determination of tocopherol. -SCBT Publication Review
Date published: 2015-05-30
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