Doxycycline monohydrateAn antimicrobial agent and a matrix metalloproteinase inhibitor

Doxycycline monohydrate (CAS 17086-28-1)

Doxycycline monohydrate | CAS 17086-28-1 is rated 5.0 out of 5 by 1.
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Application: An antimicrobial agent and a matrix metalloproteinase inhibitor
CAS Number: 17086-28-1
Purity: ≥98%
Molecular Weight: 462.45
Molecular Formula: C22H24N2O8•H2O
* Refer to Certificate of Analysis for lot specific data (including water content).
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Doxycycline monohydrate is a synthetic tetracycline derivative with similar antimicrobial activity. Animal studies suggest that it may cause less tooth staining than other tetracyclines. It is used in some areas for the treatment of chloroquine-resistant falciparum malaria (MALARIA FALCIPARUM).

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in dilute acids, alkali hydroxides, and DMSO (0.9-1.10 mg/ml). Insoluble in water.
Storage :
Store at room temperature
Melting Point :
167-168° C
Refractive Index :
n20D ~1.74 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
54684461
MDL Number :
MFCD02682958
EC Number :
209-271-1
SMILES :
C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O

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Certificate of Analysis

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Doxycycline monohydrate  Product Citations

See how others have used Doxycycline monohydrate. Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 27783893  Daer, R. et al. 2016. ACS Synth Biol.

PMID: # 23644654  Rapino, F. et al. 2014. Oncogene. 33: 1713-24.

Citations 1 to 2 of 2 total

Can this compound be used for cell culture?

Asked by: two2igm05
Thank you for your question. Doxycycline monohydrate cannot be used for cell culture.
Answered by: Technical Support
Date published: 2017-02-23
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Rated 5 out of 5 by from Duivenvoorden WC; et al Duivenvoorden WC; et al. (PubMed ID: 9949290) Doxycycline monohydrate has cytotoxic activity against some breast cancer cell lines. -SCBT Publication Review
Date published: 2015-04-26
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